Results 271 to 280 of about 297,749 (354)

Health-economic challenges for new Alzheimer's disease treatments. [PDF]

J Prev Alzheimers Dis
Fu J, Sköldunger A, Bradshaw A, Broulíková HM, Brück CC, Chapel JM, Grimm S, Hansson A, Herring WL, Hlávka J, Hoang MT, Jönsson L, Landeiro F, Mar J, McKean A, Misik M, Neumann P, Rapp T, Ritchie C, Schiel A, Sun Y, Trépel D, Trueman D, van der Veere PJ, van Rosmalen L, Vonsy JL, Walker L, Wimo A, Winblad B, Xia X, Handels R.   +30 more
europepmc   +1 more source

Comparative Oligo‐FISH Mapping Illuminates Chromosomal Evolution Among Rutaceae Species Diverged Over 50 Million Years

Advanced Science, EarlyView.
Oligonucleotide‐based fluorescence in situ hybridization probes were developed in the model citrus species Citrus maxima. These probes were applied to comparative karyotyping across 14 species in the Rutaceae family. This analysis revealed chromosomal evolution in lineages that diverged from Citrus nearly 52 million years ago.
Li He, Hainan Zhao, Xiaoxue Zeng, Zujun Yang, Wenting Li, Guoyan Zhang, Guangrong Li, Jian He, Bin Guan, Jiming Jiang   +9 more
wiley   +1 more source

Suicidal Thoughts and Self-Harm Behavior During the COVID-19 Pandemic in the United Kingdom: A Repeated Cross-Sectional Population-Based Survey Study. [PDF]

Health Sci Rep
Lombardo C, Guo L, Martin S, Crepaz-Keay D, Boss M, Thorpe L, Solomon S, Morton A, Davidson G, Kousoulis AA, Van Bortel T.   +10 more
europepmc   +1 more source

Dose‐Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload

Advanced Science, EarlyView.
This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li, Yaoqiu Wu, Guangyu Yang, Jingyi Lai, Xiaoyue Sun, Liyan Wang, Xiaoli Li, Jing Zhang, Qingxue Zhang, Hui Chen, Haiyan Lin, Bingxiang Xu, Junfeng Zhang, Hailong Wang, Anming Meng, Chunwei Cao   +15 more
wiley   +1 more source

A cross-sectional study to determine if a family history of osteoporosis impacts on attitudes towards osteoporosis knowledge, beliefs and self-efficacy in middle-aged women from the United Kingdom and Ireland.

, 2018
Ava Cronly
openalex   +1 more source

Atypical lung carcinoid with prominent mucinous stroma: unusual pathologic finding in pulmonary carcinoid. [PDF]

Oxf Med Case Reports
AlSugair GS, Althakfi WA.
europepmc   +1 more source

Stress History Establishes a Transient Tolerant State That Shapes Antibiotic Survival Upon Resuscitation

Advanced Science, EarlyView.
High‐throughput single‐cell analysis of resuscitating bacteria reveals a starvation‐history‐dependent transiently tolerant subpopulation that survives β$\beta$‐lactam exposure by temporarily reducing growth. Distinct from classical persisters, these actively growing yet dynamically modulated cells dominate survival across clinically relevant antibiotic
Kieran Abbott, Georgeos Hardo, Ruizhe Li, Jack Bradley, Ashraf Zarkan, Somenath Bakshi   +5 more
wiley   +1 more source

Clusters in craniofacial microsomia and microtia according to facial morphology and craniofacial anomalies. [PDF]

Eur J Pediatr
Ronde EM, de Jong GA, Nolte JW, Nienhuijs MEL, Bulstrode NW, Maal TJJ, Becking AG, Breugem CC, 3DCFMM research consortium.   +8 more
europepmc   +1 more source