Results 81 to 90 of about 3,712,940 (298)

Limits of a competitive authoritarianism in security policies: interpreting Türkiye’s approach towards the EU [PDF]

open access: yesFilozofija i Društvo
Middle powers are often states that support and follow democratic principles, demonstrating such atonement in the domestic and foreign policies. However, states that want to emerge in modern multipolarity prefer a more centralised approach ...
Lavezzo Edoardo
doaj   +1 more source

Japonia jako "middle power"

open access: yes, 2023
Japonia, która do 1945 roku była mocarstwem kolonialnym, w okresie powojennym zaznaczyła swoją pozycję na arenie międzynarodowej jako potęga gospodarcza. Koniec zimnej wojny doprowadził do rozpoczęcia w tym kraju dyskusji na temat jego miejsca we współczesnym świecie.
openaire   +3 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

The urban middle class in the instability of new democracies [PDF]

open access: yes
The recent revolts of the middle class in the national capitals of the Philippines and Thailand have raised a new question about democratic consolidation.
Kawanaka, Takeshi
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

South Korea amid US-China strategic competition: strategy and limitations of a middle power

open access: yesRevista CIDOB d'Afers Internacionals
This is an analysis of the evolution of South Korea’s foreign policy amid intensifying US-China strategic competition. From a neoclassical realist framework, it examines the strategies of the Lee, Park, Moon and Yoon administrations (2008-2025 ...
Just Castillo Iglesias   +1 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

A New Stage of the Italian Policy in Central Asia [PDF]

open access: yesСовременная Европа
The article examines the policy of the Italian Republic in Central Asia, which received additional impetus with the beginning of the Russian-Ukrainian conflict.
E.S. Alekseenkova
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

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