Results 111 to 120 of about 1,817,169 (313)
School Lunch Waste Among Middle School Students [PDF]
American Journal of Preventive Medicine, 2013 Juliana F.W. Cohen +4 more
openaire +1 more source
The Status of Middle Schools in the Southeastern United States: Perceptions and Implementation of the Middle School Model [PDF]
, 2019 For more than 100 years, education communities have debated how best to educate the young adolescent. Proponents of both the junior high school model and the current middle school model have advocated for a specialized approach to educating adolescents ...
Alverson, Ryan +3 more
core +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
The Impact of Alternative Grade Configurations on Student Outcomes through Middle and High School [PDF]
We use statewide administrative data from Florida to estimate the impact of attending public schools with different grade configurations on student achievement through grade 10.
Guido Schwerdt, Martin R. West
core +3 more sources
Who Stays and Who Leaves? Findings from a Three-Part Study of Teacher Turnover in NYC Middle Schools [PDF]
, 2013 This paper synthesizes findings from the Research Alliance's investigation of teacher turnover in New York City's public middle schools. These years are widely recognized as a critical turning point for students, and the NYC Department of Education (DOE)
Vanessa Coca, William H. Marinell
core
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
A Study of Adolescent Depression Among Middle School Students [PDF]
, 2006 Adolescent depression and teenage suicide should not be neglected and underestimated. While mental health is one of the ten health indicators that Healthy People 20 I 0 is focused on, and there are goals for the health community to work on, statistics ...
Lee, Cristina
core +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source