Results 1 to 10 of about 28,866 (195)

Aberrant Growth of the Anterior Cranial Base Relevant to Severe Midface Hypoplasia of Apert Syndrome [PDF]

Maxillofacial Plastic and Reconstructive Surgery, 2018
Background A 9-year-old male showed severe defects in midface structures, which resulted in maxillary hypoplasia, ocular hypertelorism, relative mandibular prognathism, and syndactyly. He had been diagnosed as having Apert syndrome and received a surgery
Suk Keun Lee, Sang Shin Lee, In San Jang
exaly   +8 more sources

Matrix Gla Protein Deficiency Impairs Nasal Septum Growth, Causing Midface Hypoplasia [PDF]

Journal of Biological Chemistry, 2017
Genetic and environmental factors may lead to abnormal growth of the orofacial skeleton, affecting the overall structure of the face. In this study, we investigated the craniofacial abnormalities in a mouse model for Keutel syndrome, a rare genetic disease caused by loss-of-function mutations in the matrix Gla protein (MGP) gene.
Marc D McKee, Faleh Tamimi, Mathieu Ferron   +2 more
exaly   +7 more sources

Foramen magnum stenosis and midface hypoplasia in C-type natriuretic peptide-deficient rats and restoration by the administration of human C-type natriuretic peptide with 53 amino acids. [PDF]

PLoS ONE, 2019
C-type natriuretic peptide (CNP)-knockout (KO) rats exhibit impaired skeletal growth, with long bones shorter than those in wild-type (WT) rats. This study compared craniofacial morphology in the CNP-KO rat with that in the Spontaneous Dwarf Rat (SDR), a
Takafumi Yotsumoto, Naomi Morozumi, Mayumi Furuya, Toshihito Fujii, Keisho Hirota, Yohei Ueda, Kazumasa Nakao, Shigeki Yamanaka, Kazunori Yoshikiyo, Sayaka Yoshida, Tomonari Nishimura, Yasuyuki Abe, Toshimasa Jindo, Hiroyuki Ogasawara, Akihiro Yasoda   +14 more
doaj   +3 more sources

Septal chondrocyte hypertrophy contributes to midface deformity in a mouse model of Apert syndrome

Scientific Reports, 2021
Midface hypoplasia is a major manifestation of Apert syndrome. However, the tissue component responsible for midface hypoplasia has not been elucidated.
Bong-Soo Kim, Hye-Rim Shin, Hyun-Jung Kim, Heein Yoon, Young-Dan Cho, Kang-Young Choi, Je-Yong Choi, Woo-Jin Kim, Hyun-Mo Ryoo   +8 more
doaj   +2 more sources

Wide Alveolar Cleft and Midface Distraction: Report of a Case

Journal of Oral Biology and Craniofacial Research, 2012
Background: Cleft lip and palate patients often present wide alveolar cleft and midface hypoplasia. Closure of such wide alveolar clefts may be difficult using bone graft.
Divya Mehrotra
exaly   +3 more sources

Positive Impact of Frontofacial Advancement on Intracranial Volumes in Patients With Syndromic Craniofaciosynostosis [PDF]

Plastic and Reconstructive Surgery, Global Open
Background:. Le Fort (LF) III midface distraction osteogenesis is one of the main techniques for correcting midface deficiency encountered in craniofaciosynostosis.
Guillaume Lacroix, MD, Mélodie-Anne Karnoub, MD, Alexis Wolber, MD, Véronique Martinot, MD, PhD, Pierre Guerreschi, MD, PhD   +4 more
doaj   +2 more sources

Apert Syndrome: A Case Report [PDF]

Iranian Journal of Neonatology, 2022
Background: Primary craniosynostosis is a form of premature fusion of the cranial sutures, which commonly occurs prenatally. The condition appears in both syndromic and nonsyndromic forms.Case report: The cause of most cases of primary craniosynostosis ...
Shahin Mafinejad, Hojat Ehteshammanesh, Ghasem Bayani, Hosein Mahmoodzade   +3 more
doaj   +1 more source

Crouzon Syndrome Spanning Three Generations: Advances in the Treatment of Syndromic Midface Deficiency

Plastic and Reconstructive Surgery, Global Open, 2023
Background:. Crouzon syndrome is an autosomal dominant genetic disorder characterized by craniosynostosis, midface retrusion, and exophthalmos. Over the past century, the treatment of craniofacial disorders like Crouzon syndrome has evolved significantly.
Kelly A. Harmon, BS, Jennifer Ferraro, MD, MBA, Nikki Rezania, BA, Taly Carmona, BHS, Alvaro A. Figueroa, DDS, MS, Christina Tragos, MD   +5 more
doaj   +1 more source

Clinical Features in Patients with Xq23 Microdeletion: A Case Report and Literature Review

JCRPE, 2022
Xq22.3-q23 microdeletion is a rare genomic disorder. The purpose of this study was to emphasize the correlation between clinical phenotype and genotype of proximal deletion on chromosome Xq22.3-q23. A 5 years old boy had a 671 KB microdeletion on Xq23 by
Lu Qin, Fei-Zhou Zhang, Jian-Hai Lv, Lan-Fang Tang   +3 more
doaj   +1 more source

A RED system guiding stent to accurately mimic the pre-planned distraction vector; a case report study new after resubmission [PDF]

Minia Journal of Medical Research, 2023
. The RED system is one of the most effective midface distractors in maxillary deficiency of cleft patients. However, determining the correct vector and accurately transferring it to the patient is incompetent and time consuming.
Khaled Barakat, Khaled Mohamed
doaj   +1 more source