Results 91 to 100 of about 318,139 (404)

Induction of chronic migraine phenotypes in a rat model after environmental irritant exposure [PDF]

open access: yes, 2017
Air pollution is linked to increased emergency department visits for headache and migraine patients frequently cite chemicals or odors as headache triggers, but the association between air pollutants and headache is not well understood.
Hurley, Joyce Harts   +4 more
core   +1 more source

Buried Treasure? Overlooked and Newly Discovered Evolutionary Contributions to Human Brain Diseases

open access: yesAnnals of Neurology, EarlyView.
Recapitulative schema of different exploratory levels of the evolutionary impact on human neurological diseases. Clinical neuroscience focuses on the mechanisms of brain function, but this approach falls short of insights into how the central nervous system (CNS) evolved, both in health and disease.
Nico J. Diederich   +20 more
wiley   +1 more source

Association Between Vestibular Migraine and Migraine Headache: Yet to Explore. [PDF]

open access: yes, 2020
ObjectivesTo evaluate if patients with a diagnosis of vestibular migraine (VM) by the International Classification of Headache Disorders (ICHD) criteria have meaningful differences in symptomatology and disease characteristics when compared to patients ...
Abouzari, Mehdi   +5 more
core  

European headache federation guideline on the use of monoclonal antibodies acting on the calcitonin gene related peptide or its receptor for migraine prevention

open access: yesThe Journal of Headache and Pain, 2019
Background and aimMonoclonal antibodies acting on the calcitonin gene-related peptide or on its receptor are new drugs to prevent migraine. Four monoclonal antibodies have been developed: one targeting the calcitonin gene-related peptide receptor ...
S. Sacco   +6 more
semanticscholar   +1 more source

Manual acupuncture versus sham acupuncture and usual care for prophylaxis of episodic migraine without aura: multicentre, randomised clinical trial

open access: yesBritish medical journal, 2020
Objective To assess the efficacy of manual acupuncture as prophylactic treatment for acupuncture naive patients with episodic migraine without aura. Design Multicentre, randomised, controlled clinical trial with blinded participants, outcome assessment ...
Shabei Xu   +13 more
semanticscholar   +1 more source

A randomized, placebo‐controlled trial of hydroxychloroquine in incomplete lupus

open access: yesArthritis &Rheumatology, Accepted Article.
Objectives Patients with features of systemic lupus erythematosus (SLE) who do not fulfill classification criteria can be designated as incomplete lupus (ILE). This condition includes individuals with a high risk of progression to SLE. Treatment of ILE may reduce symptoms, severity and incidence of SLE. Methods Hydroxychloroquine (HCQ) was chosen as an
Nancy J. Olsen   +14 more
wiley   +1 more source

Serial systemic immune inflammation indices: markers of acute migraine events or indicators of persistent inflammatory status?

open access: yesThe Journal of Headache and Pain
Background Migraine is the most common complex neurological disorder, affecting over a billion people worldwide. Neurogenic inflammation has long been recognized as a key factor in the pathophysiology of migraine though little research has been directed ...
Tissa Wijeratne   +8 more
doaj   +1 more source

Migraine in patients with rheumatoid arthritis and its relation to disease activity

open access: yesThe Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2021
Background The comorbidity between rheumatoid arthritis (RA) and migraine is complex and not completely understood. Objective This study aimed to evaluate migraine frequency in patients with RA and its relation to disease activity.
Hassan Abd-Elaty El-Sonbaty   +3 more
doaj   +1 more source

Ubrogepant for the Treatment of Migraine.

open access: yesNew England Journal of Medicine, 2019
BACKGROUND Ubrogepant is an oral, small-molecule calcitonin gene-related peptide receptor antagonist for acute migraine treatment. METHODS We conducted a randomized trial to evaluate the efficacy, safety, and side-effect profile of ubrogepant.
D. Dodick   +6 more
semanticscholar   +1 more source

Guidelines of the International Headache Society for controlled trials of preventive treatment of migraine attacks in episodic migraine in adults

open access: yesCephalalgia, 2020
Clinical trials are a key component of the evidence base for the treatment of headache disorders. In 1991, the International Headache Society Clinical Trials Standing Committee developed and published the first edition of the Guidelines for Controlled ...
H. Diener   +14 more
semanticscholar   +1 more source

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