Results 131 to 140 of about 124,603 (293)
Abstract Topiramate (TPM) is a broad‐spectrum antiepileptic drug (AED) commonly prescribed for approved and off‐label uses. Routine monitoring is suggested for clinical usage of TPM in special population due to its broad side effect profile. Therefore, it is crucial to further explore its pharmacokinetic characteristics.
Shuqing Chen+6 more
wiley +1 more source
ABSTRACT Rimegepant is a small‐molecule calcitonin gene‐related peptide receptor antagonist approved for acute and preventive migraine treatment in adults, administered as an orally disintegrating tablet (ODT). A population pharmacokinetic analysis was performed to describe rimegepant's plasma concentration‐time course and to estimate covariate effects
Craig M. Comisar+9 more
wiley +1 more source
In a metabolomics study of over 200 metabolites in 1721 fertile‐aged women, we found that current use of combined oral contraceptives (COC), especially third‐generation and other COCs, is associated with altered levels of several metabolic measures compared to nonuse of hormonal contraception or to use of a levonorgestrel intrauterine device (LNG‐IUD).
Elena Toffol+7 more
wiley +1 more source
Migraine is a primary recurrent headache manifesting in attacks lasting 4-72 hours and aff ects 2-20% of world population. Women are more often aff ected, mostly during reproductive years. Th e migraine effects quality of life and has negative impact on working capability.
openaire
Maternal deaths from sepsis in the Nordic countries during 2005–2021: A descriptive study
We found sepsis to be the fifth leading cause of maternal deaths during 2005‐2021 in the Nordic countries. Abstract Introduction Maternal sepsis is a heterogenous condition which can arise from several different infections during and after pregnancy. Common for all etiologies is a high mortality rate.
Sedina Atic Kvalvik+8 more
wiley +1 more source
Endometriosis—The scapegoat for pelvic pain?
Abstract Cyclic and noncyclic chronic pelvic pain (CPP) represent a major problem for both affected patients and healthcare providers due to its effects on physical and mental health. In times of social media and digitalization, awareness of endometriosis as a leading cause of CPP is increasing.
Gernot Hudelist+3 more
wiley +1 more source