Results 181 to 190 of about 198,438 (310)

Cancer pain: current practice and emerging targets

open access: yesBritish Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye   +5 more
wiley   +1 more source

Translation and validation of the Migraine Interictal Burden Scale (MIBS-4) in an Italian clinical cohort. [PDF]

open access: yesNeurol Sci
Piella EM   +30 more
europepmc   +1 more source

Update on Menopause Hormone Therapy; Current Indications and Unanswered Questions

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Objective To provide clinicians involved in managing menopause with a summary of current evidence surrounding menopause hormone therapy (MHT). Design The authors evaluate and synthesize existing pooled evidence relating to MHT's clinical indications, efficacy, and safety and explore the limitations of existing data. Patients The review focuses
Annice Mukherjee, Susan R. Davis
wiley   +1 more source

Specific pre-injury migraine characteristics associated with worse concussion outcomes. [PDF]

open access: yesPLoS One
Tourigny K   +4 more
europepmc   +1 more source

Long‐term neurological and psychiatric outcomes after paediatric arterial ischaemic stroke and cerebral sinovenous thrombosis

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Arterial ischemic stroke (AIS) or cerebral sinovenous thrombosis (CSVT) is a rare but serious event in children and adolescents. A descriptive long‐term (median 16 years) follow‐up study of patients revealed an increased risk of neurological and psychiatric diagnoses after AIS or CSVT, highlighting significant morbidity compared with the general ...
Jeanette Soenderlyng Springer   +4 more
wiley   +1 more source

Developmental stuttering with common and complex phenotypes

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Aim To describe the phenotypic spectrum associated with stuttering. Method Individuals with current or resolved developmental stuttering self‐referred. Surveys assessed stuttering characteristics (onset, negative impact, family history) and health (early development, other conditions). Speech and non‐verbal intelligence were assessed using conversation
Sarah E. Horton   +6 more
wiley   +1 more source

Accelerated brain ageing in migraine: a multilevel MRI-based brain-age modelling study. [PDF]

open access: yesBrain Commun
Liu HY   +9 more
europepmc   +1 more source

Optimising the Therapeutic Window: A Systematic Review and Network Meta‐Analysis of Pregabalin Dosing Strategies for Painful Diabetic Neuropathy

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Although pregabalin is a first‐line therapy for painful diabetic polyneuropathy (PDPN), its optimal dose–response relationship remains unclear. We conducted a network meta‐analysis to evaluate the efficacy and safety of fixed pregabalin dosages in PDPN patients.
Doyun Kwon   +5 more
wiley   +1 more source

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