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Circadian Variation of Migraine Attack Onset Affects fMRI Brain Response to Fearful Faces
BackgroundPrevious studies suggested a circadian variation of migraine attack onset, although, with contradictory results – possibly because of the existence of migraine subgroups with different circadian attack onset peaks. Migraine is primarily a brain
Daniel Baksa+31 more
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The Migraine Stigma Kaleidoscope View
The stigma of migraine, despite an impressive body of data on the epidemiological of migraine and the associated disability, burden and cost of migraine to patients, has not been fully evaluated as an important factor in the chronicization of the disease
Elena Gross+2 more
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Several factors can contribute to the development and chronification of migraines, including stress, which is undoubtedly a major trigger. Beyond pharmacotherapy, other treatment methods also exist, including behavioral techniques aiming at reducing ...
Dóra Dobos+20 more
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SCN 1A /Na V 1.1 channelopathies: Mechanisms in expression systems, animal models, and human iPSC models [PDF]
Pathogenic SCN1A/NaV1.1 mutations cause well defined epilepsies, including Genetic Epilepsy with Febrile Seizures Plus (GEFS+) and the severe epileptic encephalopathy Dravet syndrome. In addition, they cause a severe form of migraine with aura, Familial Hemiplegic Migraine.
arxiv +1 more source
Introduction Depression is the most common comorbidity of migraine. The brain of migraineurs with depression shows differences compared to migraine only or depression only patients.
K. Gecse+8 more
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Background Chronic migraine (CM) is associated with substantial economic burden. Real-world data suggests that onabotulinumtoxinA treatment for CM reduces healthcare resource utilisation (HRU) and related costs.
Katja Kollewe+3 more
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Background Although migraine is one of the most investigated neurologic disorders, we do not have a perfect neuroimaging biomarker for its pathophysiology.
Andrea Edit Edes+6 more
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Atogepant for the Preventive Treatment of Migraine.
BACKGROUND Atogepant is an oral, small-molecule, calcitonin gene-related peptide receptor antagonist that is being investigated for the preventive treatment of migraine. METHODS In a phase 3, double-blind trial, we randomly assigned adults with 4 to 14
J. Ailani+7 more
semanticscholar +1 more source
BackgroundMigraine without aura (MwoA) is often mistaken for rhinosinusitis. The purpose of this study was to assess the prevalence of sinonasal symptoms, sinusitis-targeting medication use and burden of migraine in a large group of people with MwoA ...
Marcin Straburzynski+5 more
doaj +1 more source
Migraine pharmacology and brain ischemia [PDF]
Introduction: The aim of this review article was to analyze in details the mechanism of drugs’ effects in the treatment and prevention of a migraine attack, as well as to discuss the hypotheses of migraine pathogenesis.
Ruben S. Mirzoyan+9 more
doaj +3 more sources