Results 31 to 40 of about 212,880 (258)

Atogepant for the Preventive Treatment of Migraine.

open access: yesNew England Journal of Medicine, 2021
BACKGROUND Atogepant is an oral, small-molecule, calcitonin gene-related peptide receptor antagonist that is being investigated for the preventive treatment of migraine. METHODS In a phase 3, double-blind trial, we randomly assigned adults with 4 to 14
J. Ailani   +7 more
semanticscholar   +1 more source

Eptinezumab in episodic migraine: A randomized, double-blind, placebo-controlled study (PROMISE-1)

open access: yesCephalalgia, 2020
Objective To evaluate the efficacy and safety of eptinezumab, a humanized anti-calcitonin gene-related peptide monoclonal antibody, in the preventive treatment of episodic migraine.
M. Ashina   +8 more
semanticscholar   +1 more source

Selectivity in genetic association with sub-classified migraine in women. [PDF]

open access: yesPLoS Genetics, 2014
Migraine can be sub-classified not only according to presence of migraine aura (MA) or absence of migraine aura (MO), but also by additional features accompanying migraine attacks, e.g. photophobia, phonophobia, nausea, etc.
Daniel I Chasman   +6 more
doaj   +1 more source

Global, regional, and national burden and trends of migraine among women of childbearing age from 1990 to 2021: insights from the Global Burden of Disease Study 2021

open access: yesThe Journal of Headache and Pain
Background Migraine, a neurological disorder with a significant female predilection, is the leading cause of disability-adjusted life years (DALYs) in women of childbearing age (WCBA). There is currently a lack of comprehensive literature analysis on the
Jing Cen   +5 more
semanticscholar   +1 more source

Hallmarks of primary headache: part 1 – migraine

open access: yesThe Journal of Headache and Pain
Migraine is a common disabling conditions which, globally, affects 15.2% of the population. It is the second cause of health loss in terms of years lived with disability, the first among women.
A. Raggi   +39 more
semanticscholar   +1 more source

Gut-brain Axis and migraine headache: a comprehensive review

open access: yesThe Journal of Headache and Pain, 2020
The terminology “gut-brain axis “points out a bidirectional relationship between the GI system and the central nervous system (CNS). To date, several researches have shown that migraine is associated with some gastrointestinal (GI) disorders such as ...
M. Arzani   +7 more
semanticscholar   +1 more source

The Impact of Biseasonal Time Changes on Migraine

open access: yesNeurology International
Background: Changes in the daily rhythm can trigger migraine attacks. The sensitivity for triggering attacks is closely linked to the regulation of biological rhythms controlled by the hypothalamus.
Carl H. Göbel   +4 more
doaj   +1 more source

Estimation of migraine prevalence considering active and inactive states across different age groups

open access: yesThe Journal of Headache and Pain, 2023
Background Migraine is a very common headache disorder on the population level, characterized by symptomatic attacks (activity). For many people with migraine, the migraine symptoms intermittently or permanently cease during their lifetime (inactive ...
Marco Piccininni   +3 more
doaj   +1 more source

Evaluation of Galcanezumab for the Prevention of Episodic Migraine: The EVOLVE-1 Randomized Clinical Trial

open access: yesJAMA Neurology, 2018
Importance Migraine is a disabling neurological disease characterized by severe headache attacks. Treatment options reduce migraine frequency for many patients, but adverse effects lead to discontinuation in many patients.
V. Stauffer   +5 more
semanticscholar   +1 more source

Comorbid and co-occurring conditions in migraine and associated risk of increasing headache pain intensity and headache frequency: results of the migraine in America symptoms and treatment (MAST) study

open access: yesThe Journal of Headache and Pain, 2020
Background Migraine has many presumed comorbidities which have rarely been compared between samples with and without migraine. Examining the association between headache pain intensity and monthly headache day (MHD) frequency with migraine comorbidities ...
D. Buse   +8 more
semanticscholar   +1 more source

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