Results 61 to 70 of about 198,836 (264)

Complications of Migraine: Migrainous Infarction

Clinical and Experimental Hypertension, 2006
Migraine and cerebrovascular disorders are comorbid diseases and the overlap of their clinical symptoms has relevant diagnostic and therapeutic implications. The prototypic condition of this relationship is reproduced by a clinical event named migrainous infarction (MI), listed by the ICHD-II among the "complication of migraine." We discuss the ...
Marco Mauri, Giorgio Bono, Giorgio Minonzio, Angelo Maurizio Clerici   +3 more
openaire   +2 more sources

Headache Phenotype and the Psychosocial Burden of Cluster Headaches: An Analysis of Patients Prior to Hospitalization

Pain and Therapy
Introduction The specific headache phenotype, accompanying symptoms and psychological impact that lead to admission of patients with cluster headache are not yet known.
Carl Hartmut Göbel, Britta Koch, Katja Heinze-Kuhn, Axel Heinze, Anna Cirkel, Hartmut Göbel   +5 more
doaj   +1 more source

Increased activation of the pregenual anterior cingulate cortex to citalopram challenge in migraine: an fMRI study

BMC Neurology, 2019
Background The anterior cingulate cortex (ACC) is a key structure of the pain processing network. Several structural and functional alterations of this brain area have been found in migraine.
Andrea Edit Edes, Shane McKie, Edina Szabo, Gyongyi Kokonyei, Dorottya Pap, Terezia Zsombok, Mate Magyar, Eva Csepany, Gabor Hullam, Adam Gyorgy Szabo, Lajos Rudolf Kozak, Gyorgy Bagdy, Gabriella Juhasz   +12 more
doaj   +1 more source

Fremanezumab for the Preventive Treatment of Chronic Migraine

New England Journal of Medicine, 2017
BACKGROUND Fremanezumab, a humanized monoclonal antibody targeting calcitonin gene–related peptide (CGRP), is being investigated as a preventive treatment for migraine. We compared two fremanezumab dose regimens with placebo for the prevention of chronic
S. Silberstein, D. Dodick, M. Bigal, P. Yeung, P. Goadsby, Tricia Blankenbiller, M. Grozinski‐Wolff, Ronghua Yang, Yuju Ma, E. Aycardi   +9 more
semanticscholar   +1 more source

Decreased Openness to Experience Is Associated with Migraine-Type Headaches in Subjects with Lifetime Depression

Frontiers in Neurology, 2017
IntroductionMigraine and depression frequently occur as comorbid conditions, and it has been hypothesized that migraine with and without depression may have a different genetic background.
Mate Magyar, Mate Magyar, Xenia Gonda, Xenia Gonda, Dorottya Pap, Dorottya Pap, Andrea Edes, Andrea Edes, Attila Galambos, Attila Galambos, Daniel Baksa, Daniel Baksa, Natalia Kocsel, Natalia Kocsel, Edina Szabo, Edina Szabo, Gyorgy Bagdy, Gyorgy Bagdy, Rebecca Elliott, Rebecca Elliott, Gyongyi Kokonyei, Gyongyi Kokonyei, Gabriella Juhasz, Gabriella Juhasz, Gabriella Juhasz, Gabriella Juhasz   +25 more
doaj   +1 more source

Chronic Migraine Pathophysiology and Treatment: A Review of Current Perspectives

Frontiers in Pain Research, 2021
Chronic migraine is a disabling neurological disorder that imposes a considerable burden on individual and socioeconomic outcomes. Chronic migraine is defined as headaches occurring on at least 15 days per month with at least eight of these fulfilling ...
Tiffani J. Mungoven, Luke A. Henderson, Noemi Meylakh   +2 more
doaj   +1 more source

The Prevalence and Impact of Migraine and Severe Headache in the United States: Figures and Trends From Government Health Studies

Headache, 2018
In this targeted systematic review, we aimed to identify up‐to‐date prevalence estimates of migraine and severe headache in adults from population‐based US government surveys. Our goal was to assess the stability of prevalence estimates over time, and to
R. Burch, P. Rizzoli, E. Loder
semanticscholar   +1 more source

Differences in treatment response between migraine with aura and migraine without aura: lessons from clinical practice and RCTs

The Journal of Headache and Pain, 2019
Migraine is a major public health problem afflicting approximately 10% of the general population and is a leading cause of disability worldwide, yet our understanding of the basis mechanisms of migraine remains incomplete.
Jakob Møller Hansen, Andrew Charles
doaj   +1 more source

Linking a genetic defect in migraine to spreading depression in a computational model [PDF]

, 2014
Familial hemiplegic migraine (FHM) is a rare subtype of migraine with aura. A mutation causing FHM type 3 (FHM3) has been identified in SCN1A encoding the Nav1.1 Na$^+$ channel. This genetic defect affects the inactivation gate. While the Na$^+$ tail currents following voltage steps are consistent with both hyperexcitability and hypoexcitability, in ...
arxiv   +1 more source

Towards dynamical network biomarkers in neuromodulation of episodic migraine [PDF]

, 2013
Computational methods have complemented experimental and clinical neursciences and led to improvements in our understanding of the nervous systems in health and disease. In parallel, neuromodulation in form of electric and magnetic stimulation is gaining increasing acceptance in chronic and intractable diseases.
arxiv   +1 more source