Results 61 to 70 of about 212,880 (258)
Scientific Reports, 2022 Altered periaqueductal gray matter (PAG) functional connectivity contributes to brain hyperexcitability in migraine. Although tryptophan modulates neurotransmission in PAG projections through its metabolic pathways, the effect of plasma tryptophan on PAG
Kinga Gecse +13 more
doaj +1 more source
Cephalalgia, 2018 Introduction Galcanezumab is a humanized monoclonal antibody binding calcitonin gene-related peptide, used for migraine prevention. Methods A global, double-blind, 6-month study of patients with episodic migraine was undertaken with 915 intent-to-treat ...
V. Skljarevski +5 more
semanticscholar +1 more source
The Journal of Headache and PainBackground Migraine is the most common complex neurological disorder, affecting over a billion people worldwide. Neurogenic inflammation has long been recognized as a key factor in the pathophysiology of migraine though little research has been directed ...
Tissa Wijeratne +8 more
doaj +1 more source
Migraine in patients with rheumatoid arthritis and its relation to disease activity
The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2021 Background The comorbidity between rheumatoid arthritis (RA) and migraine is complex and not completely understood. Objective This study aimed to evaluate migraine frequency in patients with RA and its relation to disease activity.
Hassan Abd-Elaty El-Sonbaty +3 more
doaj +1 more source
CGRP and the Trigeminal System in Migraine
Headache, 2019 The goal of this narrative review is to provide an overview of migraine pathophysiology, with an emphasis on the role of calcitonin gene‐related peptide (CGRP) within the context of the trigeminovascular system.
S. Iyengar +3 more
semanticscholar +1 more source
Migraine, Migraine Features, and Cardiovascular Disease [PDF]
Headache: The Journal of Head and Face Pain, 2010 ( Headache 2010;50:1031‐1040) Background.— Many studies support an association between migraine and cardiovascular disease (CVD).
Schürks, Markus +2 more
openaire +2 more sources
Storage of Information and Its Implications for Human Development: A Dialectic Approach
Frontiers in Psychology, 2020 How has the storage of information shaped human cognition? We bring together current advances in cognitive science, the neurobiology of memory, and archeology to explore how storage of information affects consciousness. These fields strongly suggest that
Gregorio Zlotnik, Aaron Vansintjan
doaj +1 more source
The Journal of Headache and Pain, 2021 Background Galcanezumab, a humanized monoclonal antibody that binds calcitonin gene-related peptide, has demonstrated a significant reduction in monthly migraine headache days compared with placebo. Here, we analyze data from 3 randomized clinical trials
Michael Ament +6 more
doaj +1 more source
Ubrogepant for the Treatment of Migraine.
New England Journal of Medicine, 2019 BACKGROUND Ubrogepant is an oral, small-molecule calcitonin gene-related peptide receptor antagonist for acute migraine treatment. METHODS We conducted a randomized trial to evaluate the efficacy, safety, and side-effect profile of ubrogepant.
D. Dodick +6 more
semanticscholar +1 more source
British medical journal, 2020 Objective To assess the efficacy of manual acupuncture as prophylactic treatment for acupuncture naive patients with episodic migraine without aura. Design Multicentre, randomised, controlled clinical trial with blinded participants, outcome assessment ...
Shabei Xu +13 more
semanticscholar +1 more source