Results 61 to 70 of about 59,781 (255)

Rimegepant for the acute treatment of migraine: a systematic review and meta-analysis

The Journal of Headache and Pain
Objective To determine the efficacy and tolerability of a single 75 mg oral dose of rimegepant compared with placebo for the acute treatment of migraine attacks in adults.
Melissa Istoc, Basit A. Chaudhry, Rune H. Christensen, Haidar M. Al-Khazali, Messoud Ashina, William K. Karlsson, Håkan Ashina   +6 more
doaj   +1 more source

Trait Rumination Influences Neural Correlates of the Anticipation but Not the Consumption Phase of Reward Processing

Frontiers in Behavioral Neuroscience, 2017
Cumulative evidence suggests that trait rumination can be defined as an abstract information processing mode, which leads people to constantly anticipate the likely impact of present events on future events and experiences. A previous study with remitted
Natália Kocsel, Natália Kocsel, Natália Kocsel, Edina Szabó, Edina Szabó, Edina Szabó, Attila Galambos, Attila Galambos, Attila Galambos, Andrea Édes, Andrea Édes, Dorottya Pap, Rebecca Elliott, Rebecca Elliott, Lajos R. Kozák, György Bagdy, György Bagdy, Gabriella Juhász, Gabriella Juhász, Gabriella Juhász, Gyöngyi Kökönyei, Gyöngyi Kökönyei   +21 more
doaj   +1 more source

MIGRAINE [PDF]

The Journal of Nervous and Mental Disease, 1875
n ...
openaire   +1 more source

Genetic Variants of Na+,K+‐ATPase Associated With Neurological Disorders: A Systematic Review

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Neurological disorders encompass a wide range of severe symptoms and manifestations, many of which are associated with genetic variants that affect ionic homeostasis. Na+,K+‐ATPase, a transmembrane enzyme responsible for maintaining electrochemical gradients in cells, plays a crucial role in neuronal excitability and brain function.
Giovana Kummer da Rosa, Leandro Rodrigo Ribeiro, Jéssica Lorena Bariviera, Mauro Schneider Oliveira   +3 more
wiley   +1 more source

Effective Improvement of Symptoms in Patients with Acute Migraine by GR43175 Administered in Dispersible Tablets [PDF]

, 1989
GR43175, a selective 5-HT1-like agonist, was administered as oral dispersible tablets in an open, uncontrolled dose-ranging study to assess its efficacy as an agent for acute migraine.
Dönicke, A., Melchart, D., Bayliss, E.M.   +2 more
core   +1 more source

The EXPLAIN Study: Exploring Arthrogryposis Multiplex Congenita in Adults in Norway — A Description of Demographic, Medical, and Neurological Findings

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Arthrogryposis Multiplex Congenita (AMC) encompasses several hundred conditions with diverse genetic, pathophysiological, and clinical origins. The overarching EXPLAIN study explores underlying causes and implications of AMC and represents the largest clinical cohort of adults with AMC reported to date.
My Vuong Hermansen, Kristin Ørstavik, Unni Steen, Mathias Toft, Cathrine Brunborg, Lena Lande Wekre   +5 more
wiley   +1 more source

Increased activation of the pregenual anterior cingulate cortex to citalopram challenge in migraine: an fMRI study

BMC Neurology, 2019
Background The anterior cingulate cortex (ACC) is a key structure of the pain processing network. Several structural and functional alterations of this brain area have been found in migraine.
Andrea Edit Edes, Shane McKie, Edina Szabo, Gyongyi Kokonyei, Dorottya Pap, Terezia Zsombok, Mate Magyar, Eva Csepany, Gabor Hullam, Adam Gyorgy Szabo, Lajos Rudolf Kozak, Gyorgy Bagdy, Gabriella Juhasz   +12 more
doaj   +1 more source

Storage of Information and Its Implications for Human Development: A Dialectic Approach

Frontiers in Psychology, 2020
How has the storage of information shaped human cognition? We bring together current advances in cognitive science, the neurobiology of memory, and archeology to explore how storage of information affects consciousness. These fields strongly suggest that
Gregorio Zlotnik, Aaron Vansintjan
doaj   +1 more source

Expanded characterization of the valproic acid zebrafish larval model of autism spectrum disorder: Insights into dysregulation in the gut

Animal Models and Experimental Medicine, EarlyView.
Meticulous calculation of zebrafish‐equivalent therapeutic valproic acid (VPA) dosage maximized the translational value of the data. Hyposerotonergic tone underpinned an anxiety‐like outcome as a core symptom of autism spectrum disorder (ASD). Compartment‐specific dopaminergic and serotonergic dysregulation in the brain versus gut provided mechanistic ...
Lesha Pretorius, Johanna Adriana Coetzee, Alexio Pedro dos Santos, Carine Smith   +3 more
wiley   +1 more source

Therapeutic role of melatonin in migraine prophylaxis: Is there a link between sleep and migraine?

, 2020
Melatonin is a ubiquitously distributed molecule that possesses diverse functions. Melatonin plays a key role in the endogenous circadian rhythms of humans via light stimulation in the hypothalamus.
주민경, Byung-Su Kim, 송태진, Tae-Jin Song, Min Kyung Chu   +4 more
core   +2 more sources