Results 201 to 210 of about 140,721 (366)

Sleep disorders in migraine

open access: diamond, 2021
N. V. Vashchenko   +2 more
openalex   +2 more sources

Migraine in mitochondrial disorders [PDF]

open access: yesGeneral Internal Medicine and Clinical Innovations, 2018
Sinda Zarrouk-Mahjoub, Josef Finsterer
openaire   +1 more source

“When my mind hurts, my body hurts”: Complex PTSD and chronic physical health conditions—A qualitative study exploring the factors contributing to their relationship

open access: yesBritish Journal of Clinical Psychology, EarlyView.
Abstract Objectives Complex PTSD (cPTSD) has a high comorbidity rate with chronic physical health conditions. This is the first qualitative study to investigate what factors might be contributing to this relationship. Methods Twelve participants with cPTSD and chronic physical health conditions were recruited from mental health services across London ...
Laura Blackett   +3 more
wiley   +1 more source

Long‐term efficacy and safety of mitapivat in non‐transfusion‐dependent α‐ or β‐thalassaemia: An open‐label phase 2 study

open access: yesBritish Journal of Haematology, EarlyView.
Mitapivat is an oral activator of pyruvate kinase (PK), the enzyme responsible for the final step in glycolysis, and increases production of adenosine triphosphate (ATP), which may lead to improvements in red blood cell health, ineffective erythropoiesis and haemolysis.
Kevin H. M. Kuo   +9 more
wiley   +1 more source

Headache And Hormones

open access: yesAnnals of Indian Academy of Neurology, 2002
There are many reasons to suggest a link between headache and hormones. Migraine is three times common in women as compared to men after puberty, cyclic as well as non-cyclic fluctuations in sex hormone levels during the entire reproductive life span of
Shukla Rakesh
doaj  

ERNEST COST action overview on the (patho)physiology of GPCRs and orphan GPCRs in the nervous system

open access: yesBritish Journal of Pharmacology, EarlyView.
G protein‐coupled receptors (GPCRs) are a large family of cell surface receptors that play a critical role in nervous system function by transmitting signals between cells and their environment. They are involved in many, if not all, nervous system processes, and their dysfunction has been linked to various neurological disorders representing important
Necla Birgül Iyison   +15 more
wiley   +1 more source

Progress on the development of Class A GPCR‐biased ligands

open access: yesBritish Journal of Pharmacology, EarlyView.
Class A G protein‐coupled receptors (GPCRs) continue to garner interest for their essential roles in cell signalling and their importance as drug targets. Although numerous drugs in the clinic target these receptors, over 60% GPCRs remain unexploited. Moreover, the adverse effects triggered by the available unbiased GPCR modulators, limit their use and
Paula Morales   +20 more
wiley   +1 more source

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