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The Lancet, 1981
The hypothesis that migraine is caused by a primary abnormality of platelet behaviour was investigated in a total of 77 migraine patients and control subjects. Platelets taken from patients with classical migraine during a headache-free period demonstrated significantly higher spontaneous platelet aggregation and platelet adhesion than platelets from ...
B. Wachowicz +3 more
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The hypothesis that migraine is caused by a primary abnormality of platelet behaviour was investigated in a total of 77 migraine patients and control subjects. Platelets taken from patients with classical migraine during a headache-free period demonstrated significantly higher spontaneous platelet aggregation and platelet adhesion than platelets from ...
B. Wachowicz +3 more
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The Lancet, 1978
It is suggested that a primary abnormality of platelet function can account for the diverse clinical, biochemical, and pathological findings reported in migraine.
C.W.M Whitty +5 more
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It is suggested that a primary abnormality of platelet function can account for the diverse clinical, biochemical, and pathological findings reported in migraine.
C.W.M Whitty +5 more
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Migraine as a Cortical Brain Disorder
Headache: The Journal of Head and Face Pain, 2020PurposeMigraine is an exclusively human chronic disorder with ictal manifestations characterized by a multifaceted clinical complexity pointing to a cerebral cortical involvement. The present review is aimed to cover the clinical, neuroimaging, and neurophysiological literature on the role of the cerebral cortex in migraine pathophysiology ...
Piero Barbanti +5 more
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Migraine and movement disorders
Neurological Sciences, 2012A large series of clinical and experimental observations on the interactions between migraine and the extrapyramidal system are available. Some previous studies reported high frequency of migraine in some basal ganglia (BG) disorders, such as essential tremor (ET), Tourette's syndrome (TS), Sydenham's chorea and more recently restless legs syndrome ...
B. Lecce +7 more
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Migraine and rare neurological disorders
Neurological Sciences, 2020Although migraine is generally considered an idiopathic and isolated neurological condition, it may also represent the presenting symptom of several uncommon heritable and acquired neurological diseases contributing to the recognition of such conditions.
Scelzo E. +6 more
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Archives of Neurology, 1986
The voluminous scientific literature on the subject of migraine is typical of a disorder of unknown cause. Consequently, it has become difficult to ascertain whether the complexities of the syndrome reflect the nature of the disorder or the multiplicity of causal theories.
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The voluminous scientific literature on the subject of migraine is typical of a disorder of unknown cause. Consequently, it has become difficult to ascertain whether the complexities of the syndrome reflect the nature of the disorder or the multiplicity of causal theories.
openaire +5 more sources
Migraine: A disorder of metabolism?
Medical Hypotheses, 2016The treatment and prevention of migraine within the last decade has become largely pharmacological. While there is little doubt that the advent of drugs (e.g. triptans) has helped many migraine sufferers to lead a normal life, there is still little knowledge with respect to the factors responsible for precipitating a migraine attack.
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Migraine: a complex genetic disorder [PDF]
The Lancet Neurology, 2007 Although family and twin studies show that there is a genetic component to migraine, no genes predisposing to common forms of the disorder have been identified. The most encouraging findings have emerged from the identification of genes causing rare mendelian traits that phenotypically resemble migraine.
Roel A. Ophoff +4 more
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Pathophysiology of Migraine Disorder
2021Despite migraine being described for thousands of years, the pathophysiology of this disorder is still not completely understood. Migraine is a form of sensory dysfunction, with many manifestations (Pathophysiology and Genetics of Migraine. Headache. p. 88–99; Goadsby et al., Physiol Rev 97(2):553–622, 2017).
Natasha Acosta Diaz +2 more
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Migraine as a systemic disorder
Neurology, 2007The neurovascular theory of migraine integrates the phenomena of head pain (due to vascular inflammation and dilation) and aura (cortical neuronal spreading depression), which precedes or accompanies headache in a sizable minority. The trigeminal nerves play a prominent role, emanating from the brainstem and innervating the vasculature, although the ...
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