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Migraine and Neurogenetic Disorders

Current Pain and Headache Reports, 2013
In the current classification of headache disorders, headache attributable to genetic disorders is not classified separately, rather as headache attributed to cranial or cervical vascular disorder. The classification thus implies that a vascular pathology causes headache in these genetic disorders.
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Migraine: A Psychosomatic Disorder

Headache: The Journal of Head and Face Pain, 1977
SYNOPSIS Migraine has no single cause. It can be seen as a reaction of the organism, probably determined by the hypothalamus and released by a variety of extrinsic and intrinsic factors. Several factors may determine attacks at different times within a patient's lifetime.
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Posttraumatic Stress Disorder in Migraine

Headache: The Journal of Head and Face Pain, 2009
Objective.— To evaluate the relative frequency of posttraumatic stress disorder (PTSD) in episodic migraine (EM) and chronic daily headache (CDH) sufferers and the impact on headache‐related disability. Background.— Approximately 8% of
B Lee, Peterlin   +6 more
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MIGRAINE: A BLOOD DISORDER?

The Lancet, 1978
It is suggested that a primary abnormality of platelet function can account for the diverse clinical, biochemical, and pathological findings reported in migraine.
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Migraine Disorder

AAOHN Journal, 2007
Migraine disorder is disabling, costly, underdiagnosed, and undertreated. It affects employees' quality of life and ability to work or attend school, potentially decreasing their earning ability. Migraine disorder impacts the workplace substantially through absenteeism and presenteeism and increases health care costs.
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Migraine Without Aura and Migraine with Aura are Inherited Disorders

Cephalalgia, 1996
The familial occurrence and mode of inheritance were analysed in families with migraine without aura (MO) and migraine with aura (MA). The probands were found among 4000 persons from the general population. All persons with MA were included as probands, and an equivalent number of probands with MO was selected as a random sample among those with MO ...
M B, Russell, L, Iselius, J, Olesen
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Pathophysiology of Migraine Disorder

2021
Despite migraine being described for thousands of years, the pathophysiology of this disorder is still not completely understood. Migraine is a form of sensory dysfunction, with many manifestations (Pathophysiology and Genetics of Migraine. Headache. p. 88–99; Goadsby et al., Physiol Rev 97(2):553–622, 2017).
Bridget Mueller   +2 more
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Migraine is not primarily a vascular disorder

Cephalalgia, 2012
There is no question that significant vascular changes may occur during a migraine attack. The question is whether these vascular phenomena are a cause or a consequence of migraine pathophysiology and migraine symptoms. While the simplistic appeal of the ‘vascular hypothesis’ of migraine has had remarkable staying power, studies of the clinical ...
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Vestibular disorders in patients with migraine

European Archives of Oto-Rhino-Laryngology, 1997
Vestibular symptoms frequently occur in patients with migraine headache. The common migraine is defined in neurology as a unilateral, pulsating headache, which may be associated with nausea and vomiting, and lasts one or several days. In the classic form patients have visual prodromal symptoms. Focal neurological signs in the migraine complique include,
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Migraine: A disorder of metabolism?

Medical Hypotheses, 2016
The treatment and prevention of migraine within the last decade has become largely pharmacological. While there is little doubt that the advent of drugs (e.g. triptans) has helped many migraine sufferers to lead a normal life, there is still little knowledge with respect to the factors responsible for precipitating a migraine attack.
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