Results 41 to 50 of about 5,586,127 (221)
The interictal transcriptomic map of migraine without aura. [PDF]
J Headache PainAbstract Background The present study aimed to deliver a replicable transcriptomic map of migraine without aura (MO) and its comprehensive, genome- and drug discovery focused analysis to identify hypotheses for future research- and clinical attempts.
Petschner P +9 more
europepmc +4 more sources
Genetic Variants of Na+,K+‐ATPase Associated With Neurological Disorders: A Systematic Review
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.ABSTRACT Neurological disorders encompass a wide range of severe symptoms and manifestations, many of which are associated with genetic variants that affect ionic homeostasis. Na+,K+‐ATPase, a transmembrane enzyme responsible for maintaining electrochemical gradients in cells, plays a crucial role in neuronal excitability and brain function.
Giovana Kummer da Rosa +3 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Zavegepant nasal spray, a calcitonin gene‐related peptide receptor antagonist indicated for acute treatment of migraine with or without aura in adults, is a substrate for organic anion transporting polypeptide 1B3 (OATP1B3), Na+/taurocholate cotransporting polypeptide (NTCP), P‐glycoprotein (P‐gp), and cytochrome P450 3A4 (CYP3A4).
Alice Ke +8 more
wiley +1 more source
A Case of Migraine Aura Status in a Migraine Patient With Typical Aura Without Headache
Cureus, 2023 Migraine aura status (MAS) is a rare complication of migraine and is listed in the appendix of the International Classification of Headache, Third Edition. MAS occurs in migraine with aura (MwA) patients, with at least three auras occurring over a period of three days.
openaire +2 more sources
Effect of migraine on suicide mortality in young adults: a nationwide cohort study in South Korea
BMJ Mental HealthBackground Migraine is linked to increased suicidal behaviour, but its relationship with suicide mortality remains underexplored. In South Korea, suicide rates are among the highest in Organisation for Economic Co-operation and Development nations ...
Mi Ji Lee +3 more
doaj +1 more source
What general practitioners need to know about patent foramen ovale [PDF]
, 2014 A patent foramen ovale (PFO) consists of a hole between the right and left atriums of the heart that did not close the way it should after birth. Twenty five percent of the population have a PFO, but this usually does not cause problems, because the ...
Saliba, Mario
core
The association between diabetes and migraine: a systematic review and meta-analysis
Headache MedicineIntroduction Diabetes and migraine are prevalent conditions that can significantly impact quality of life. Existing review suggests a possible connection between the two, though findings have varied.
Heba Ramadan
doaj +1 more source
Could calcitonin gene‐related peptide inhibitors prevent status epilepticus?
Epilepsia, EarlyView.Abstract Calcitonin gene‐related peptide (CGRP) inhibitors modulate pain and neuroinflammation, a recognized contributor to epileptogenesis and status epilepticus (SE). We examined the association between CGRP inhibitor use and SE hospitalization in epilepsy patients with comorbid migraine.
Michael Nsaka +6 more
wiley +1 more source
, 1999 Migraine is a complex neurovascular disease characterised by episodic attacks of severe headache accompanied by autonomic and neurological symptoms. Two types of migraine have been identified: (1) common migraine, or migraine without aura, occurring in ...
Farrugia, Isabelle
core
Epilepsia Open, EarlyView.Abstract Migraine and epilepsy frequently coexist, but evidence on the safety of calcitonin gene‐related peptide (CGRP)‐targeting therapies in people with epilepsy is lacking. We evaluated long‐term migraine and epilepsy outcomes in a real‐world multicenter retrospective cohort of adults with comorbid migraine and epilepsy treated with anti‐CGRP ...
Marina Romozzi +13 more
wiley +1 more source