Results 41 to 50 of about 3,016 (138)

High‐altitude headache: Insights into pathophysiology and potential treatment implications

The Journal of Physiology, EarlyView.
Abstract figure legend High‐altitude headache occurs during prolonged exposure to low oxygen, such as during ascent to high altitude. Several risk factors increase its likelihood, with the degree of hypoxia, often driven by rapid ascent to greater altitudes, being the most prominent factor.
Marika Falla, Florian Frank, Giacomo Strapazzon, Justin Lawley   +3 more
wiley   +1 more source

Visual migraine aura with or without headache: association with right to left shunt and assessment following transcutaneous closure

, 2012
M Khalid Mojadidi,1 Hamidreza Khessali,1 Rubine Gevorgyan,1 Ralph D Levinson,2 Jonathan M Tobis11Division of Interventional Cardiology, David Geffen School of Medicine, University of California at Los Angeles, 2Division of Comprehensive Ophthalmology and
Khessali H, Gevorgyan R, Mojadidi MK, Levinson RD, Tobis JM   +4 more
core  

Genetics of migraine aura: an update

, 2020
Migraine is a common brain disorder with a large genetic component. Of the two main migraine types, migraine with aura and migraine without aura, the genetic underpinning in the former is least understood.
Boer, I. de, Maagdenberg, A.M.J.M. van den, Terwindt, G.M.   +2 more
core   +1 more source

Population Pharmacokinetics and Exposure‐Response Analyses for Ubrogepant Efficacy and Safety in the Acute Treatment of Migraine: Analysis of Phase 1–3 Studies

The Journal of Clinical Pharmacology, Volume 66, Issue 6, June 2026.
Abstract A population pharmacokinetic (popPK) model was developed for ubrogepant using data from 10 Phase 1, 1 Phase 2, and 2 Phase 3 studies. The data were described by a 2‐compartment model with linear elimination and transit compartment absorption. Formulation, food intake, race, gender, and hepatic impairment had a statistically significant impact ...
Sven Stodtmann, Lucia Siovitz, Heiko Babel, Ramesh R. Boinpally   +3 more
wiley   +1 more source

Headache psychiatry: A structured narrative review and integrative framework

Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 2, June 2026.
Headache disorders are among the most prevalent and disabling neurological conditions worldwide, yet their psychiatric comorbidities remain systematically underrecognized in clinical practice. This narrative review introduces Psychocephalology—a biopsychosocial framework conceptualizing headache through five interacting domains: neurobiology, pain ...
Kyohei Otani
wiley   +1 more source

Temperamental characteristics in childhood migraine without aura: a multicenter study

, 2013
Maria Esposito,1 Rosa Marotta,2 Beatrice Gallai,3 Lucia Parisi,4 Giuseppina Patriciello,1 Serena Marianna Lavano,2 Giovanni Mazzotta,5 Michele Roccella,4 Marco Carotenuto11Center for Childhood Headache, Clinic of Child and Adolescent Neuropsychiatry ...
Lavano SM, Marotta R, Mazzotta G, Esposito M, Patriciello G, Parisi L, Roccella M, Carotenuto M, Gallai B   +8 more
core  

A 58‐year‐old woman experiencing occasional dizziness, impaired awareness, and deep feeling of fear

Brain Pathology, EarlyView.
Alessandro Selvaggini, Sabrina Rossi, Marco Brollo, Sabina Barresi, Laurino Licia, Lorenzo Nicolè   +5 more
wiley   +1 more source

What's Needed for a Migraine Cost‐Of‐Illness Study in Aotearoa New Zealand: Review of Data Sources and Gaps

Journal of the Royal Society of New Zealand, Volume 56, Issue 3, June 2026.
Cost of illness (COI) studies are used to quantify the economic burden of disease on health systems, employers and society, and identify where costs may be saved by improvements in disease management. Many migraine COI studies have been published internationally but none have included data from Aotearoa New Zealand (NZ), despite the known high ...
Fiona Imlach, Sofiia Tsaregorodtseva, Maite Irurzun‐Lopez, William Leung, Calvin Chan, Ray Bose   +5 more
wiley   +1 more source

Investigating Bidirectional Causal Relationships Between Imaging‐Derived Brain Phenotypes and Sedative‐Hypnotic Use Disorder: A Mendelian Randomization Study

Addiction Biology, Volume 31, Issue 6, June 2026.
Using bidirectional two‐sample Mendelian randomisation across 3935 brain imaging‐derived phenotypes, we causally linked specific neuroimaging features to sedative‐hypnotic use disorder (SHUD) susceptibility. Increased cortical thickness in temporal‐limbic regions and altered default mode network connectivity conferred risk, whereas larger brainstem ...
Liqin Lu, Guoxin Zhuang, Jue Deng, Siheng Huang, Liang Meng, Fenglan Li, Xiaoli Zhu   +6 more
wiley   +1 more source

Efficacy, IHS Guideline Adherence, and Methodological Quality of Noninvasive Neuromodulation Clinical Trials in Migraine and Cluster Headache: A Systematic Review

European Journal of Neurology, Volume 33, Issue 6, June 2026.
ABSTRACT Background Noninvasive neuromodulation has emerged as a promising approach for acute and preventive treatment of migraine and cluster headache. This systematic review evaluates how noninvasive neuromodulation trials align with guidelines by the International Headache Society (IHS), their efficacy on IHS‐recommended outcomes, and the robustness
Javiera Canales‐Rodríguez, Cornelius Angerhöfer, Edoardo Caronna, Bianca Raffaelli, Lucas Hendrik Overeem, Patricia Pozo‐Rosich, Uwe Reuter   +6 more
wiley   +1 more source