Results 111 to 120 of about 531,325 (290)
The Influence of Stocks and Flows on Migrants’ Location Choices [PDF]
We examine the determinants of a current migrant's location choice emphasizing the relative importance and interaction of migrant stocks and flows. We show that both stocks and flow have significant impacts on the migrant’s decision of where to locate ...
Gil S. Epstein +2 more
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Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Reverse migration and the health emergency among Afghan returnees: a call for regional action
International Journal for Equity in HealthThe current geopolitical situation in the Middle East suggests a growing trend of reverse migration, where migrants and refugees may be gradually returned to their home countries.
Seyed Aria Nejadghaderi +5 more
doaj +1 more source
A Deadly Journey for Children: The Central Mediterranean Migration Route [PDF]
, 2017 A new report from UNICEF - 'A Deadly Journey for Children: The Central Mediterranean Migrant Route' - provides an in-depth look at the extreme risks facing refugee and migrant children as they make the perilous journey from sub-Saharan Africa into Libya ...
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The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
The Economic Drivers of Human Trafficking: Micro-Evidence from Five Eastern European Countries.. [PDF]
Human trafficking is a humanitarian problem of global scale, but quantitative research on the issue barely exists. This paper is a first attempt to explore the economic drivers of human trafficking and migrant exploitation using micro data. We argue that
Omar Mahmoud, Toman, Trebesch, Christoph
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Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Discursive Approaches to the Reception of Non-EU Migrants in Polish Official Political Discourse
Central and Eastern European Migration ReviewPoland has faced several crisis situations related to migration in the past decade. With differences in the scale and origins of incoming people, these crises have triggered various reactions from Polish policy-makers, from the welcoming of non-EU ...
Claire Laurent, Elodie Thevenin
doaj +1 more source
No. 70: International Migrants and Refugees in Cape Town’s Informal Economy [PDF]
, 2015 This report is the most comprehensive study yet of the contribution of migrant and refugee entrepreneurs to Cape Town’s local economy. The survey of over 500 entrepreneurs engaged in trade, services and manufacturing in different areas of the city ...
Chikanda, Abel +3 more
core +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source