Results 151 to 160 of about 1,750,893 (334)

A Hydrodynamic Bioreactor for High‐Yield Production of Extracellular Vesicles from Stem Cell Spheroids with Defined Cargo Profiling

open access: yesAdvanced Science, EarlyView.
This study harnesses hydrodynamic flows to generate, confine and stimulate stem cell spheroids, enabling the large‐scale production of extracellular vesicles (EVs). This innovative method not only streamlines spheroid formation and subsequent EV release in a single, integrated process, but also ensures the generation of EVs with enhanced biological ...
Solène Lenoir   +7 more
wiley   +1 more source

Associations of latent patterns of parent‒child communication with communication quality and mental health outcomes among Chinese left-behind children

open access: yesBMC Public Health
Background Parent‒child communication in migrant families is essential to family bonds and the mental health of left-behind children (LBC). Little is known about the different patterns of communication between migrant parents and LBC and associated ...
Qian-Wen Xie   +5 more
doaj   +1 more source

No. 56: Right to the Classroom: Educational Barriers for Zimbabweans in South Africa [PDF]

open access: yes, 2011
This report examines the obstacles to access by Zimbabwean children and students to schools and tertiary institutions in South Africa. There is a common assumption in South Africa that these children and students have no right to an educa­tion in South ...
Crush, Jonathan, Tawodzera, Godfrey
core   +1 more source

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

open access: yesAdvanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim   +6 more
wiley   +1 more source

Red Blood Cells Internalize Extracellular DNA via Apoptotic Bodies with Clinical Relevance to Cancer Patients

open access: yesAdvanced Science, EarlyView.
Mature red blood cells (RBCs) can capture extracellular DNA, with short fragments homologous to cfDNA. This uptake is mediated by apoptotic bodies, which induce RBC oxidative stress, deformation, and accelerated in vivo clearance. The rbcDNA abundance correlates with tumor burden and therapeutic response, highlighting its potential as a liquid biopsy ...
Zihang Zeng   +20 more
wiley   +1 more source

The Communication Patterns Between Parents And Migrant Children in The Digital Era: Strengthening Emotional Connections Through Technology

open access: yesBaileo
This study aims to analyze the communication patterns between parents and migrant children in the digital era, as well as the impact on their emotional connection.
Celvin Yhosep Sinaga   +2 more
doaj   +1 more source

Paul Hamlyn Foundation and Unbound Philanthropy Supported Options Initiative: Evaluation of Phase One [PDF]

open access: yes, 2015
The Supported Options Initiative is one element of the Paul Hamlyn Foundation's Social Justice programme, delivered in partnership with Unbound Philanthropy (the Foundations). The first phase of the Initiative ran for two years from 2012.
Ben Cairns, Leila Baker, Ravi Kohli
core  

Low YTHDC1 Expression Upregulates FSCN1 to Promote Nuclear F‐Actin Formation and Facilitate Double‐strand DNA Breaks Repair in TMZ‐Resistant Glioblastoma

open access: yesAdvanced Science, EarlyView.
This study revealed that low expression of YTHDC1 in TMZ‐resistant GBM cells leads to increased FSCN1 expression, which is suppressed by m6A modification. FSCN1 activates the CDC42/N‐WASP/Arp2/3 axis in the cell nucleus by recruiting the guanine nucleotide exchange factor (GEF) family member FGD1, thereby promoting F‐actin polymerization in the nucleus.
Minglong Yang   +9 more
wiley   +1 more source

Migrant Children and Integration-Related Challenges in Lithuania: The Opinions of Educators (A Case Study)

open access: yesSocial Sciences
The number of migrant children in Lithuania is increasing every year. For many years, the majority of migrants (around 82%) were returning Lithuanians, but since 2022, due to the ongoing war between Ukraine and Russia, a large influx of Ukrainian ...
Grazina Ciuladiene
doaj   +1 more source

Home - About - Disclaimer - Privacy