Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
PERILAKU SOSIAL MAHASISWA MIGRAN DI SEKITARKAMPUS III UNIVERSITAS MUHAMMADIYAH MALANG(Studi Tentang Gaya Hidup dan Pola Interaksi Sosial) [PDF]
At this time the third campus of UMM students amounts to approximately 23,500 students who come from various corners of the country as migrant students from Kalimantan, Sulawesi and NTB / NTT.
Muthmainah, Iin
core
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Student migrant, refugee or both? [PDF]
Tertiary education institutions in resettlement and asylum countries across the world are asking what role they can and should play in responding to today’s forced displacement crises. Exploring and better understanding opportunities within higher education to provide pathways to protection should be a priority. Studies on education migration show that
openaire +2 more sources
From vocational training to education: the development of a no-frontiers education policy for Europe? [PDF]
This article focuses on developments towards an EU educational policy. Education was not included as one of the Community competencies in the Treaty of Rome.
Barnard C. +20 more
core +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
The best of both worlds? Online ties and the alternating use of social network sites in the context of migration [PDF]
While an ever-growing body of research is concerned with user behavior on individual social network sites (SNSs)—mostly Facebook—studies addressing an alternating use of two or more SNS are rare.
Binder, JF, Sutcliffe, AG
core +2 more sources
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Career guidance and counselling (CGC) plays an important role in the ‘egalitarian tradition’ of the Nordic countries’ perspective of education, since it aims to support all students in developing skills and knowledge to access further education and the ...
Alessandra Aldrovandi +2 more
doaj +1 more source

