Results 111 to 120 of about 296,708 (302)
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
The Impact of Worker Effort on Public Sentiment Towards Temporary Migrants [PDF]
Temporary and circular migration programs have been devised by many destination countries and supported by the European Commission as a policy to reduce welfare and social costs of immigration in destination countries.
Epstein, Gil S., Venturini, Alessandra
core +4 more sources
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Dissociation as a mechanism of psychological defense in adapting to a different cultural environment
Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева, 2018 In the theoretical part, the authors focus on specific issues in the diagnosis and treatment of patients migrants with dissociative symptoms related to the cultural specialty of the settings in the etiology of emerging symptoms and for psychotherapeutic ...
N. A. Bokhan +2 more
doaj
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Journal of Modern ScienceObjectives The contribution aims to carry out a socio-anthropological and juridical analysis of the issues concerning the status of migrants and refugees, in order to identify the strategies prepared by the Italian State regarding the protection of the ...
Salvatore Piliu
doaj +1 more source
Settlement Patterns and the Geographic Mobility of Recent Migrants to New Zealand [PDF]
Twenty-three percent of New Zealand's population is foreign-born and forty percent of migrants have arrived in the past ten years. Newly arriving migrants tend to settle in spatially concentrated areas and this is especially true in New Zealand.
David C. Maré +2 more
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Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Other Whites, White Others: East European Migrants and the Boundaries of Whiteness [PDF]
, 2015 This thesis examines the integration experiences of East European migrants to England using the theoretical framework of Critical Whiteness Studies.
Halej, JO
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