Results 141 to 150 of about 678,010 (343)

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Neighbourhood segregation and social mobility among the descendants of Middlesbrough's 19th century Celtic immigrants [PDF]

open access: yes, 2004
This paper is one of a series of research papers which form part of an ESRC funded research project on?The Quantitative Analysis of Family Names?. The purpose of this project is to assess the contribution thatinformation on the geographic distribution of
Webber, R
core  

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Forced Migration, The Human Face of a Health Crisis [PDF]

open access: yes, 2015
Nearly 60 million refugees, asylum-seekers and internally displaced persons (IDPs) fled their homes in 2014, predominately from war-torn Syria, Afghanistan and Somalia. The global response to assisting this vulnerable group has been wholly incommensurate
Gostin, Lawrence O., Roberts, Anna E.
core   +2 more sources

Imperial strategy of cancer cells through mitochondrial transfer

open access: yesMolecular Oncology, EarlyView.
Cangkrama et al. demonstrated that cancer cells donate their mitochondria to fibroblasts through mitochondrial transfer, reprogramming them into ‘MitoCAF’. Likewise, our group has identified mitochondrial transfer from cancer cells to tumor infiltrating lymphocytes, resulting in mitochondrial ‘hijack’ and impaired antitumor immunity.
Takamasa Ishino, Yosuke Togashi
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

RURAL-URBAN MIGRATION IN BOLIVIA: AN ESCAPE BOAT? [PDF]

open access: yes
This paper studies rural-urban migration in Bolivia. Domestic migration usually works as an equalization mechanism, in which regions with fewer economic opportunities send migrants to more dynamic regions.
Donald Pianto   +2 more
core  

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