Results 121 to 130 of about 2,228,529 (317)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

The role of internal and international relative deprivation in global migration: DEMIG project paper no. 5

, 2011
This paper analyses the role of internal (within-country) and international (bilateral and global) relative deprivation and absolute deprivation in international migration.
Czaika, Mathias, de Haas, Hein
core  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Youth in Dubrava

Migracijske i etničke teme, 1998
The goal of the international project ''lnternationales Lernen" is a comparative study on individual orientations and social representation among youth in five European countries: Germany, the Netherlands, Greece, Latvia and Croatia.
Melita Švob, Carmen Brčić, Sonja Podgorelec   +2 more
doaj  

Migration as cause and consequence of aspirations : DEMIG project paper no. 13

, 2012
This paper aims to disentangle the relationship between aspirations and migration by analysing why Indonesian internal migrants generally have higher aspirations when compared with non-migrants.
Czaika, Mathias
core  

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

The determinants of international migration: conceptualizing policy, origin and destination effects: DEMIG project paper no. 2

, 2011
The effectiveness of migration policies has been widely contested in the face of their supposed failure to steer immigration and their hypothesized unintended, counter-productive effects.
de Haas, Hein
core  

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Migration Dilemmas of Islanders: Commuting Leading to Migration or Remaining at Home

Migracijske i etničke teme, 2001
The paper presents and discusses the results of an empirical survey carried out in April 2000 on the islands Prvić, Zlarin and Krapanj in the Šibenik coastal area.
Ivan Lajić, Sonja Podgorelec, Dragutin Babić   +2 more
doaj  

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source