Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
Migration, trade, capital, and development: substitutes, complements, and policies [PDF]
The economic migration of people has lagged substantially behind that of capital and trade. That's largely because barriers to the movement of people remain high.
Gustav Ranis
core
Inter-regional Migration: The UK experience [PDF]
This paper looks at the scenario of intra-UK migration amongst its four regions. The level of intra-UK migration is significant and is increasing over time. Using several measures of the balance in migration we observe that, broadly speaking, the balance
Biswas, T., McHardy, J., Nolan, M.A.
core
Understanding and measuring mechanical signals in the tumor stroma
This review discusses cancerâassociated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
FĂ tima de la Jara Ortiz+3 more
wiley +1 more source
Commentary on session IV: The historical relationship between migration, trade, and development [PDF]
Commentary on the three papers in this session: "Inequality and schooling responses to globalization forces: lessons from history" by Jeffrey G. Williamson; "Trade, migration, and economic development: the risks and rewards of openness" by James F ...
Barry R. Chiswick
core
Inward FDI, Remittances, and Out-migration [PDF]
In this study, we look at the relationship between remittances received at home, inward Foreign Direct Investment (FDI) and out-migration of individuals with different levels of education. Using the bilateral international migration data in 1990 and 2000,
Wang, Miao Grace, Wong, M. C. Sunny
core +1 more source
3D Migration Aperture and Formula Connecting Dips of Prestack Time Migrated and Unmigrated Data [PDF]
Formula connecting dips of unmigrated 2D and prestack time migrated constant offset gathers was recently proposed (Singh, 2024). A handy formula for 2D prestack migration aperture was also derived. We extend the same work to the 3D case, that is, we derive prestack time migration aperture, and formula connecting dips as a function of dip of a planar ...
arxiv
A potential tumor suppressor role of PLK2 in glioblastoma
PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia+5 more
wiley +1 more source
Studies of the Action of Electrolytes on Bacteria. Part II. The Influence of the Trivalent Positive Salts on the Rate of Migration of Bacteria in an Electric Field, and their Effect on Growth and Virulence of Pathogenic Organisms. [PDF]
Cresswell Shearer
openalex +1 more source
Globalization and Mexican labor markets [PDF]
North American economic integration has had potentially positive implications for Mexican workers, and the perceived competition between Mexican and U.S. workers may not be as accurate as popularly believed.
Raymond Robertson
core