Results 41 to 50 of about 4,228,165 (285)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Human Migration and Human Migration Algorithmic Perspective

open access: yesInternational Journal of Applied Sciences and Radiation Research
Human migration is a complex phenomenon driven by socioeconomic, political, environmental, and demographic factors. Understanding and modeling migration patterns have become vital for planning, humanitarian response, and sustainable development. In parallel, nature-inspired optimization algorithms have gained attention for solving complex real-world ...
Mitat Uysal, Aynur Uysal, Elif Erçelik
openaire   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

open access: yesMolecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau   +9 more
wiley   +1 more source

Labour Migration for Vulnerable Communities: A Strategy to Adapt to a Changing Environment [PDF]

open access: yes, 2011
de Moor N. Labour Migration for Vulnerable Communities: A Strategy to Adapt to a Changing Environment. COMCAD Arbeitspapiere - Working Papers, 101.
Moor, Nicole de, de Moor, Nicole
core  

Algorithms for automated live migration of virtual machines

open access: yesJournal of Systems and Software, 2015
Two live migration strategies for load balancing, "pull" and "push", are investigatedThe two strategies complement each otherThe push strategy will not perform well if the system load level is very highThe migration strategies can re-balance the system in 4-15 min We present two strategies to balance the load in a system with multiple virtual machines (
Mattias Forsman   +3 more
openaire   +3 more sources

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

Migration as an Adaptation Strategy and Its Consequences on Coastal Society: Experience from Bangladesh [PDF]

open access: yes, 2011
Mallick B. Migration as an Adaptation Strategy and Its Consequences on Coastal Society: Experience from Bangladesh. COMCAD Arbeitspapiere - Working Papers, 96.
Mallick, Bishawjit
core  

Fast radar detection algorithm based on two‐dimensional non‐uniform trilinear autocorrelation function for manoeuvring target with jerk motion

open access: yesElectronics Letters, 2021
This letter presents a fast detection algorithm based on a two‐dimensional non‐uniform trilinear autocorrelation function for the manoeuvring target with jerk motion.
Zhongying Liang   +3 more
doaj   +1 more source

Optimal algorithms for page migration in dynamic networks

open access: yesJournal of Discrete Algorithms, 2009
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Bienkowski, Marcin   +3 more
openaire   +5 more sources

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