Results 101 to 110 of about 472,776 (289)
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Nordicum-Mediterraneum, 2015 Review of the following book: Pieter Bevelander & Bo Petersson (eds.), Crisis and Migration. Implications of the Eurozone Crisis for Perceptions, Politics, and Policies on Migration, Lund: Nordic Academic Press ...
Giorgio Baruchello
doaj
Should we be concerned about Venezuelan hemorrhagic fever? - A reflection on its current situation in Venezuela and potential impact in Latin America amid the migration crisis. [PDF]
New Microbes New Infect, 2021 Rodríguez-Morales AJ +4 more
europepmc +1 more source
, 2019 Never in history has so much attention been paid to human movement. Global migration yields demographic shifts of historical significance, profoundly shaking up world politics – as shown by the “refugee crisis,” the rise of White nationalism in the United States, and the spreading of the populist right in Europe. Global migration is one of the defining
ORGAD, Liav, RUBINSTEIN, Amnon
openaire +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
The concept of crisis migration
Forced Migration Review, 2014 "Crisis migration needs to be understood in terms of ‘tipping points’, which are triggered not just by events but also by underlying structural processes.
Jane McAdam
doaj
Impact of the Global Financial Crisis on Migration and Remittances [PDF]
Remittances to developing countries are estimated to have declined by 6.1 percent in 2009 as a result of weak job markets in major destination countries. Although new migration has fallen, it is still positive.
Mohapatra, Sanket, Ratha, Dilip
core
From Migration Hub to Asylum Crisis: The Changing Dynamics of Contemporary Migration in Yemen [PDF]
, 2014 Historically, Yemen has been a country of emigration, immigration and transit. The fate of Yemeni society has been tied to emigration, as well as to the presence and activities of a Yemeni diaspora scattered throughout the world, in the Gulf countries ...
Thiollet, Hélène
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source