Results 131 to 140 of about 2,615,163 (352)
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
The concept of crisis migration
Forced Migration Review, 2014 "Crisis migration needs to be understood in terms of ‘tipping points’, which are triggered not just by events but also by underlying structural processes.
Jane McAdam
doaj
Climate Change, Migration, and Conflict: Addressing Complex Crisis Scenarios in the 21st Century [PDF]
, 2012 Outlines how climate change, migration, and conflict intersect in Africa, Asia, and the Americas and implications for national, human, and environmental security.
Laura Conley, Michael Werz
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
HERMENEUTICS OF THE MIGRATION CRISIS
Iustinianus Primus Law Review, 2018 In the following pages, I will try to examine how and why do juridical and political decisions on life and death of others incorporated as refugees in our contemporary times produce disposable lives, that are not recognized as worth living, and death ...
Viki Mladenova
doaj
European Borders in Turbulent Times: The Case of the Central Mediterranean ‘Extended Borderland’
Politeja, 2017 This article presents one of the most salient aspects of the migration crisis in the EU, namely the turbulent management of external borders, and analyzing it in the case of the central region of the Mediterranean Sea.
Artur Gruszczak
doaj +1 more source
, 2019 Foreigners go home! This is a reverberating chorus at the heart of the migration crisis everywhere in the world. This call manifests itself in the recurring xenophobic or Afrophobic attacks directed at foreign nationals in South Africa.
T. D. Mashau
semanticscholar +1 more source
Failed Securitisation Moves during the 2015 ‘Migration Crisis’
International migration (Geneva. Print), 2019 The EU has tried to distinguish itself as respecting human rights in its migration policies. In 2015, mass drownings at sea of refugees from war-torn and despotic countries like Syria and Eritrea started to rise with the end of Mare Nostrum, the Italian ...
H. Hintjens
semanticscholar +1 more source
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
The elephant in Europe’s living room: why the EU’s crisis summit must tackle the root causes of migration [PDF]
, 2015 EU ministers are due to meet on 14 September for an emergency summit on the ongoing migration crisis. Ruben Zaiotti writes that the real focus of the meeting should be on addressing the root causes of migration.
Zaiotti, Ruben
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