Results 151 to 160 of about 2,615,163 (352)
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Migrants and imported disease: Trends of admission in an Italian infectious disease ward during the migration crisis of 2015-2017. [PDF]
BMC Public Health, 2020 Del Puente F +5 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Comparative Population Studies, 2012 Since the start of the global economic downturn,GermanyandSpainhave experienced highly-divergent impacts of the crisis on the labour market in general and on immigrant workers in particular.
Dirk Godenau +3 more
doaj
Migration crisis: Macedonia on crossroads
, 2015 Abstract Macedonia is witnessing the largest migrant crisis which is driving an unprecedented number of people going on life-threatening journeys to safety. At his point we can say that Macedonian as well as the European Union’s common policy on asylum lacks solidarity and consistency to deal with this problem.
Kosevaliska, Olga +2 more
openaire +3 more sources
Migration, remittances and the current economic crisis: implications for Central and Eastern Europe [PDF]
In recent years labour migration from Central and Eastern Europe has increased, resulting in a comparatively stable and high inflow of remittances into these countries.
Barbara Dietz
core
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Should I Stay or Should I Go? Romanian Migrants during Transition and Enlargements [PDF]
, 2014 The change in Romanian political regime in 1989 has lifted the barriers for population circulation and mobility that were further more amplified in 2002 by the liberalization of Romanians' circulation in the Schengen space.
Andrén, Daniela, Roman, Monica
core
Aging and Cancer, EarlyView.ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source