Results 31 to 40 of about 40,998 (268)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Towards a regional agreement on environmental displacement?

Forced Migration Review, 2017
Efforts towards a regional agreement on migration in South America should be extended to recognise and protect those displaced for environmental reasons.
Erika Pires Ramos, Fernanda de Salles Cavedon-Capdeville, Lilian Yamamoto, Diogo Andreola Serraglio   +3 more
doaj  

Haití en las Américas. Puntos de quiebre en las políticas migratorias y movilidades haitianas en el continente (2010-2023)

Cuadernos Inter.c.a.mbio sobre Centroamérica y el Caribe
En este trabajo analizo el panorama regional que favoreció el despliegue de nuevas movilidades haitianas en las Américas a partir del año 2010 y hasta el año 2023 con la implementación de la aplicación digital (la CBP One) del Departamento ...
Catherine Bourgeois
doaj   +1 more source

Écrire les voix d'autres personnes : entre engagements, trahisons et réciprocités

Nouvelle Revue Synergies Canada, 2022
Dans le cadre d’une recherche en sciences humaines et sociales, collecter et transcrire des récits de personnes migrantes, par une démarche compréhensive, peut produire un effacement de leurs voix, quand bien même c’est le contraire qui serait visé ...
Delphine Leroy
doaj  

To Migrate or Not to Migrate: An Analysis of Operator Migration in Distributed Stream Processing

IEEE Communications Surveys & Tutorials
One of the most important issues in data stream processing systems is to use operator migration to handle highly variable workloads in a cost-efficient manner and adapt to the needs at any given time on demand. Operator migration is a complex process that involves changes in the state and stream management of a running query, typically without any loss
Espen Volnes, Thomas Plagemann, Vera Goebel   +2 more
openaire   +2 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Les ambivalences de l’État social-sécuritaire

Lien Social et Politiques, 2007
L’article envisage le changement du paradigme des politiques publiques liées à l’insécurité en milieu urbain. À l’encontre de ceux qui voient l’émergence d’un État pénal se substituant à l’État social, l’article soutient, à partir de l’étude de la ...
Andrea Rea
doaj   +1 more source