Results 31 to 40 of about 120,916 (311)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Le médecin et l’interprète, de la méconnaissance à la délégation. À propos d’une expérience française [PDF]
In France, most doctors have a poor knowledge of professional interpretation, and share the general concern that speaking a foreign language threatens national cohesion.
Murielle Rondeau-Lutz +2 more
doaj
Sous l’effet des politiques d’internationalisation, Singapour se positionne aujourd’hui comme l’un des pôles mondiaux de l’enseignement supérieur les plus sélectifs. Comment ces politiques se sont-elles imposées à Singapour?
Valérie Erlich, Jimmy Stef
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
A travers un panel d'expositions réalisées depuis 1980 sur les migrations, leurs histoires, leurs mémoires et les regards artistiques contemporains, ce dossier analyse les modalités de mise en oeuvre de l'exposition des migrations, les collaborations ...
Bensignor, François +30 more
core +1 more source
E-passeur.com, spectacle d’anticipation sur les migrations [PDF]
Hommes & Migrations : Quelle est la place des migrations féminines dans votre travail créatif ? Sedef Ecer : Cela fait partie de mes « thématiques-obsessions ». Depuis 2008, il y a au moins un personnage de femme migrante dans chacun de mes textes.
Poinsot, Marie
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Ce dossier explore les relations concrètes entre divers types de dégradations environnementales et les migrations de populations dans une dizaine de pays dans le monde, grâce aux résultats d'un vaste programme européen de recherche (EACH-FOR) conduit ...
Bensignor, François +30 more
core +1 more source
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source

