Results 71 to 80 of about 40,998 (268)

Sous-traitance et bureaucratisation néolibérale : une analyse de l’interface de la distance dans l’accueil des demandeurs d’asile

open access: yesLien Social et Politiques, 2019
En mettant à l’épreuve de l’ethnographie les questions posées par la sous-traitance, cet article s’intéresse à la bureaucratisation néolibérale de l’accueil des demandeurs d’asile en Suisse.
Camilla Alberti
doaj   +1 more source

« Être » et « devenir » desplazado à Soacha : les effets de catégorisation sur les sociabilités urbaines et sur la recomposition des violences dans les cinturónes de miseria(s)

open access: yesTrayectorias Humanas Trascontinentales, 2018
L’un des effets les plus visibles du conflit armé interne colombien réside dans les mouvements de population provoqués dans son sillage. Ils concernent près de sept millions deux cent mille citoyens qui se sont vus contraints de quitter leurs lieux de ...
Tiphaine Duriez
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The prohibition of the full-face veil in Belgium: between collective hysteria and symbolic policy

open access: yesRevista CIDOB d'Afers Internacionals, 2017
This article analyses the debate on the prohibition of the full-face veil in Belgium, which was finalised in a law approved in March 2010 by the Belgian Chamber of Representatives after a discussion process in the public sphere and Parliament. First, the
Corinne Torrekens
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Venezuelan displacement: a challenge to Brazil

open access: yesForced Migration Review, 2017
Brazil must strengthen its reception and integration of fleeing ...
Helisane Mahlke, Lilian Yamamoto
doaj  

La frontière étatique, terme de l’aide humanitaire ? Une analyse du droit en action

open access: yesCriminologie
Depuis la décision du Conseil constitutionnel français du 6 juillet 2018 sur la « fraternité », un acte humanitaire désintéressé est licite s’il est cantonné au territoire national et illicite s’il constitue une aide à l’entrée irrégulière sur ce ...
Bastien Charaudeau Santomauro
doaj   +1 more source

Mobilités étudiantes et territoires universitaires : vers une uniformisation des pratiques ?

open access: yesEspace populations sociétés, 2005
Since French Society enters the so-called “Economy of knowledge”, migrations of young people, especially these concerning students, are of most interest. Despite the fact that it could help to understand University as a system and ways regions can evolve,
Myriam Baron, Cathy Perret
doaj   +1 more source

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