Results 91 to 100 of about 1,679,947 (308)
Advanced Science, EarlyView.This study shows that a local, data‐driven AI model can accurately predict diverse optical and chiroptical properties of [6]helicenes using information from close structural neighbours. Combined with genetic algorithms, it enables inverse design for tailored properties, establishing practical structure–property rules for efficient molecular discovery ...
Rafael G. Uceda +8 more
wiley +1 more source
Covalent Reprogramming of Kinase Binders to Modulate Protein Abundance
Advanced Science, EarlyView.Electrophilic remodeling of a broad‐spectrum kinase binder reveals how subtle chemical changes reprogram protein fate. An acrylamide analog of a multi‐kinase binder selectively stabilizes Aurora kinase A (AURKA) by suppressing its ubiquitination, while a short‐linker variant converts this stabilizer into a degrader.
Chen Mozes +4 more
wiley +1 more source
Modification of the masses of the lightest neutral mesons in a hadronic medium under an external magnetic field [PDF]
, 2017 The effective masses of the neutral mesons in a hadronic medium and under an external magnetic field are evaluated as functions of the baryonic density and the field intensity.
Aguirre, Ricardo Miguel
core +3 more sources
Noninvasive Focal Gene Delivery into the Cerebellum of Non‐Human Primates using Focused Ultrasound
Advanced Science, EarlyView.Focal and non‐invasive viral vector delivery in non‐human primates remains a major challenge in translational neuroscience. Low‐intensity focused ultrasound was used to transiently open the blood–brain barrier and enable targeted gene delivery to the cerebellum.
Noelia Esteban‐García +11 more
wiley +1 more source
O fio de Ariadne que nos desvenda o teatro de Alves Redol
Sinais de Cena, 2013 Recensão às obras: Espelho de ver por dentro: O percurso teatral de Alves Redol de Miguel Falcão, (Lisboa, Imprensa Nacional – Casa da Moeda, 2009). Alves Redol, Teatro: Textos publicados e inéditos de Miguel Falcão (org., trad.) , (Lisboa, Imprensa ...
Maria Helena Serôdio
doaj
Advanced Science, EarlyView.A novel optical thermometer exploits the rare UV emission of Yb2+ ions in a SrB4O7 host, enabling highly sensitive, non‐contact temperature measurements from 80 to 420 K. The applied multiple linear regression (MLR) analysis results in a multiple increase in the resulting temperature sensitivity.
Fang Zhao +6 more
wiley +1 more source
Red nucleus and rubrospinal tract disorganization in the absence of Pou4f1
Frontiers in Neuroanatomy, 2015 The red nucleus is a neuronal population that plays an important role in forelimb motor control and locomotion. Histologically it is subdivided into two subpopulations, the parvocellular red nucleus located in the diencephalon and the magnocellular red ...
Jesus E. eMartinez-Lopez +5 more
doaj +1 more source
Advanced Intelligent Discovery, EarlyView.Bayesian optimization enabled the design of PA56 system with just 8 wt% additives, achieving limiting oxygen index 30.5%, tensile strength 80.9 MPa, and UL‐94 V‐0 rating. Without prior knowledge, the algorithm uncovered synergistic effects between aluminum diethyl‐phosphinate and nanoclay.
Burcu Ozdemir +4 more
wiley +1 more source
A Negatively Curved Pyrene‐Fused Azaacene
Angewandte Chemie, EarlyView.A pyrene‐fused azaacene derivative is reported in which steric overcrowding caused by eight phenyl substituents induces bending of the aromatic framework rather than twisting. ABSTRACT Non‐planar aromatic hydrocarbons display distorted π‐frameworks that give rise to unique optoelectronic properties.
Marco Carini +3 more
wiley +2 more sources
Natural Product Communications, 2016 Propolis production by honey bees is the result of a selective harvest of exudates from plants in the neighborhood of the hive. This product is used in Argentina as a food supplement and alternative medicine.
Ana Salas +4 more
doaj +1 more source