Results 171 to 180 of about 1,152,275 (289)
Cancer in Systemic Sclerosis: Clinical Associations and Prognostic Impact From the EUSTAR Registry
Arthritis &Rheumatology, EarlyView.Objective Cancer represents a major cause of death in systemic sclerosis (SSc). Established risk factors are limited to specific subsets, particularly early diffuse anti‐RNA polymerase III (POLR3)–positive disease, needing further exploration. Methods We performed a nested case‐control study within the European Scleroderma Trials and Research group ...
Antonio Tonutti +52 more
wiley +1 more source
Arthritis &Rheumatology, EarlyView.Objective Still disease (SD) is an autoinflammatory disorder characterized by remarkably high interleukin‐18 (IL‐18) levels. Increasing evidence suggests that adaptive immunity also contributes to its pathogenesis, particularly in refractory courses. Macrophage activation syndrome (MAS), one of SD's most severe complications, is associated with further
Greta Rogani +17 more
wiley +1 more source
Arthritis &Rheumatology, Accepted Article.Background Calcium pyrophosphate deposition (CPPD) disease is a heterogeneous condition and is frequently misdiagnosed due to the different clinical presentations and variable disease progression. Aim of this study is to identify clinical phenotypes of CPPD disease by integrating real‐world data from two datasets. Methods Data from the COLCHICORT trial
Greta Pellegrino +20 more
wiley +1 more source
Lateral Ulnar Collateral Ligament Reconstruction Through a Mini‐Invasive Approach
Arthroscopy Techniques, EarlyView.Abstract Posterolateral rotatory instability is the most common form of elbow instability, secondary to valgus, supination, and axial loading in elbow extension. The lateral ulnar collateral ligament (LUCL) is the primary restraint to posterolateral rotatory instability and multiple techniques of repair and reconstruction of the LUCL have been reported
Valeria Vismara +5 more
wiley +1 more source
Rectus Femoris Autograft Harvesting: Tips and Tricks
Arthroscopy Techniques, EarlyView.Abstract The rectus femoris tendon has recently emerged as a potential graft option for anterior cruciate ligament reconstruction because of its favorable biomechanical properties, substantial graft length, and minimally invasive harvest characteristics.
Riccardo D’Ambrosi +6 more
wiley +1 more source
Precision medicine in paediatrics: Progress and priorities
British Journal of Clinical Pharmacology, EarlyView.Precision medicine is revolutionizing personalized healthcare, advancing both diagnostics and therapeutics at an unprecedented pace. Reviewing the paediatric applications of pharmacometrics, pharmacogenomics and advanced therapy medicinal products highlights not only the relevance of these exciting innovations to frontline care but also the significant
Nicola Husain +3 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Definitions of ‘medicines use’ and ‘polypharmacy’ may refer to all medicines, regular long‐term medicines or another subset. Valid definitions of medicines use should incorporate type of use (long term, short course and as needed [PRN]), changes in use (start, stop and dose change) and a description of temporal examination (cross‐sectional or ...
Lorna Pairman, Paul Chin, Matthew Doogue
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Aim Critical care for COVID‐19 patients presents unique challenges, particularly in sedation management. Patients demonstrate notable dose‐related resistance to propofol, potentially due to complex pharmacokinetic alterations. Emerging evidence suggests that plasma extracellular vesicle‐associated miRNA represents valuable predictive ...
Debora Curci +10 more
wiley +1 more source
Longitudinal microcomputed tomography uncovers divergent trajectories of lung maturation in preterm and hyperoxia-exposed neonatal rabbits. [PDF]
Am J Respir Cell Mol BiolBuseghin D +8 more
europepmc +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims This study aimed to evaluate the safety, tolerability and pharmacokinetics of a novel oral modified‐release psilocybin formulation (REL‐P11) in normal‐weight and overweight/obese healthy adults and to assess its suitability for controlled, subperceptual exposure, in light of emerging evidence supporting serotonergic modulation in metabolic ...
Anna Signor +11 more
wiley +1 more source