Results 151 to 160 of about 124,113 (255)

Organelle‐Resolved Tetrazine‐trans‐Cyclooctene Click Chemistry for Cargo Delivery and Release

Chemistry – A European Journal, EarlyView.
Bioorthogonal click chemistry tools provide a means for specific intracellular conjugation of molecules. In this study, we used reactive tetrazine (Tz) and TCO moieties for labeling of organelles and organelle‐specific delivery and activation of doxorubicin prodrugs.
Oleh Durydivka, Marek Chovanec, Rastislav Dzijak, Michal Rahm, Jachym Hrusak, Paul E. Reyes‐Gutierrez, Milan Vrabel   +6 more
wiley   +1 more source

PERFECTA Loaded Lipid Cubosomes for 19F‐MRI: Physico‐Chemical Characterization

Chemistry – A European Journal, EarlyView.
Phytantriol‐based cubosomes loaded with PERFCTA, a fluorinated MRI probe, were developed as promising systems for imaging and drug delivery. The nanoparticles showed high PERFECTA encapsulation efficiency, strong fluorine MRI signals, and optimal colloidal stability in biological media.
Pietro Milesi, Beatrice Lucia Bona, Cristina Chirizzi, Marco Campanile, Pompea Del Vecchio, Marc Schmutz, Valerie Sartor, Debora Berti, Pierangelo Metrangolo, Francesca Baldelli Bombelli, Barbara Lonetti   +10 more
wiley   +1 more source

Pro-inflammatory intestinal Th17-cells are tissue-resident, accumulate in the epithelia in Crohn's disease, and predict unresponsiveness to vedolizumab. [PDF]

J Crohns Colitis
Paroni M, Faggiano C, Righetti C, Dusetti I, Ranzani V, Moschetti G, Noviello D, Vasco C, Vecchi M, Landini P, Facciotti F, Abrignani S, Caprioli F, Geginat J.   +13 more
europepmc   +1 more source

VOCs Adsorption and Exchange Properties in Bispidine‐Based Mn(II) 1D CPs Made of Orthogonally Oriented Linear Chains

Chemistry – A European Journal, EarlyView.
Combining the chiral bispidine ligand L1 with MnCl2 affords coordination polymers (CPs) with an unusual topology for this family of compounds, consisting of orthogonally packed ribbon‐like one‐dimensional (1D) chains. Their behavior was investigated through single‐crystal‐to‐single‐crystal exchange with aromatic volatile organic compounds (VOCs) and ...
Meriem Goudjil, Martina Lippi, Sara Camorali, Chiara Pelosi, Alessandro Sayed, Luca Bernazzani, Patrizia Rossi, Paola Paoli, Massimo Cametti   +8 more
wiley   +1 more source

Compact Manifolds With Unbounded Nilpotent Fundamental Groups and Positive Ricci Curvature

Communications on Pure and Applied Mathematics, EarlyView.
ABSTRACT It follows from the work of Kapovitch and Wilking that a closed manifold with nonnegative Ricci curvature has a uniformly almost nilpotent fundamental group. Leftover questions and conjectures, have asked if in this context the fundamental group is actually uniformly almost abelian. The main goal of this work is to construct examples (Mk9,gk)$(
Elia Bruè, Aaron Naber, Daniele Semola
wiley   +1 more source

Correction: A GPT-reinforced social robot for patient communication: a pilot study. [PDF]

Front Digit Health
van 't Klooster JJR, Capasso M, van Gorssel D, Vrolijk E, Rettagliata G, Gerritsen D, Hegeman M, Tauro E, Caiani EG, Vonkeman HE.   +9 more
europepmc   +1 more source

Ethical Behaviour and Corporate Financing. The Case of ‘Legality Rating’

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT The financial crisis has heightened awareness of ethical and legal issues in the business context. Corporate ethical behaviour is increasingly measured through sustainability ratings. Since 2012, in Italy, the introduction of a sustainability rating, namely the legality rating (LR), has served as an innovative ‘label’ for socially responsible ...
Federica Doni, Lucio Masserini, Zeila Occhipinti, Roberto Verona   +3 more
wiley   +1 more source

Prevalence and determinants of anxiety in amyotrophic lateral sclerosis. [PDF]

BJPsych Open
Aiello EN, De Luca G, Curti B, Torre S, Gendarini C, Cocuzza A, Colombo E, De Sandi A, Mellace D, Ferrucci R, Barbieri S, Maranzano A, Verde F, Messina S, Doretti A, Morelli C, Silani V, Ticozzi N, Poletti B.   +18 more
europepmc   +1 more source

Family Ownership and ESG Performance: The Moderating Role of Sustainability Committee and ESG‐Linked Executive Compensation

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Grounded in agency theory, this article examines the relationship between family ownership concentration and environmental, social, and governance (ESG) performance, and analyzes the moderating role of sustainable governance mechanisms. Specifically, it assesses whether sustainability committees and ESG‐linked executive compensation moderate ...
Pasquale Latella, Roberta Pisani, Fabio Quarato, Paolo Tenuta   +3 more
wiley   +1 more source

Sex-related differences in lung injury distribution and outcomes in COVID-19 acute respiratory failure: insights from the CT-COVID19 multicenter study group. [PDF]

Intensive Care Med Exp
Signori D, Nova A, Xin Y, Gerard SE, Magliocca A, Vitale G, Mussoni L, Montomoli J, Subert M, Ponti A, Spadaro S, Poli G, Casola F, Garberi R, Restivo A, Raimondi Cominesi D, Giani M, Zambelli V, Foti G, Laffey JG, Cereda M, Rezoagli E, CT-COVID19 Multicenter Study Group.   +22 more
europepmc   +1 more source