Results 131 to 140 of about 125,754 (255)

Pharmacokinetics, Effectiveness and Safety of Certolizumab Pegol in Children and Adolescents With Active Juvenile Idiopathic Arthritis: 9+‐Year Results From a Multicenter, Open‐Label Study

Arthritis &Rheumatology, EarlyView.
Objective The purpose of this study was to assess the pharmacokinetics, effectiveness, safety, and immunogenicity of certolizumab pegol (CZP) in polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods Pediatric Arthritis Study of Certolizumab Pegol (NCT01550003), a multicenter, open‐label study, enrolled patients aged 2 to 17 years with ...
Hermine I. Brunner, Lyudmila Grebenkina, Irina Nikishina, Ekaterina Alexeeva, Vyacheslav Chasnyk, Carlos Abud‐Mendoza, Nadina Rubio‐Pérez, Heinrike Schmeling, María del Rocio Maldonado‐Velázquez, Diane Brown, Andrew Zeft, Esi Morgan, C. Egla Rabinovich, Daniel Kingsbury, Hulya Bukulmez, Beth Gottlieb, Thomas Griffin, Lisa Imundo, Stacey Tarvin, Earl Silverman, Laura Shaughnessy, Saori Shimizu, Paulette Williams, Rocío Lledó‐García, Gauri Utturkar, Baran Ufuktepe, Alberto Martini, Daniel J. Lovell, Nicolino Ruperto, the Paediatric Rheumatology International Trials Organisation (PRINTO); the Pediatric Rheumatology Collaborative Study Group (PRCSG), Hermine I. Brunner, Lyudmila Grebenkina, Irina Nikishina, Ekaterina Alexeeva, Vyacheslav Chasnyk, Carlos Abud‐Mendoza, Nadina Rubio‐Pérez, Heinrike Schmeling, María del Rocio Maldonado‐Velázquez, Diane Brown, Andrew Zeft, Esi Morgan, C. Egla Rabinovich, Daniel Kingsbury, Hulya Bukulmez, Beth Gottlieb, Thomas Griffin, Lisa Imundo, Stacey Tarvin, Earl Silverman, Alberto Martini, Daniel L. Lovell, Nicolino Ruperto   +52 more
wiley   +1 more source

Updated Italian norms for the Paired-Associate Learning Test (PALT). [PDF]

Aging Clin Exp Res
Zago S, Rasi T, Aiello EN, Frisco F, De Luca G, Curti B, Moreschi A, Corso A, Difonzo T, Lorusso L, Formenti A, Tetto A, Di Rosa E, Poletti B, Bolognini N, Caffarra P.   +15 more
europepmc   +1 more source

Persistent IL‐18 fuels expansion of CD38+HLA‐DR+CD8+ T cells in Still's disease and macrophage activation syndrome

Arthritis &Rheumatology, Accepted Article.
Objective Still's disease (SD) is an autoinflammatory disorder characterized by remarkably high IL‐18 levels. Increasing evidence suggests that adaptive immunity also contributes to its pathogenesis, particularly in refractory courses. Macrophage activation syndrome (MAS), one of SD's most severe complications, is associated with further IL‐18 ...
Greta Rogani, Remco G.A. Erkens, Alejandra Bodelón, Tim R. Mocking, Marein T.M. Putmans, Freya M.C.H. Huijsmans, Lyanne J.P.M. Sijbers, Aafke M. De Ligt, Maurice J.H. Van Haaren, Rianne C. Scholman, Noël M.M. Dautzenberg, Joyce I. Meesters‐Ensing, Martina Rossano, Laura Porretti, Stefan Nierkens, Francesca S. Minoia, Sebastian J. Vastert, Jorg van Loosdregt   +17 more
wiley   +1 more source

Boosting thyroid nodule diagnosis through ultrasound and molecular imaging integration with unsupervised learning. [PDF]

Quant Imaging Med Surg
Facchinetti F, L'Imperio V, Piga I, Papetti DM, Capitoli G.   +4 more
europepmc   +1 more source

Lateral Ulnar Collateral Ligament Reconstruction Through a Mini‐Invasive Approach

Arthroscopy Techniques, EarlyView.
Abstract Posterolateral rotatory instability is the most common form of elbow instability, secondary to valgus, supination, and axial loading in elbow extension. The lateral ulnar collateral ligament (LUCL) is the primary restraint to posterolateral rotatory instability and multiple techniques of repair and reconstruction of the LUCL have been reported
Valeria Vismara, Nieto Carlos Murillo, Alfonso Carlos Gonzalez‐Delgado, Grégoire Ciais, Filip Cosic, Pierre Laumonerie   +5 more
wiley   +1 more source

Correction: Study of grapevine endophytes' interaction with the host and their potential as biocontrol agents as sustainable alternative to agrochemicals. [PDF]

Front Microbiol
Pizzi S, Canito AD, Mulero EP, Bezerra CCON, Ricciardi V, Maddalena G, Maluleke E, Foschino RC, Toffolatti SL, Fracassetti D, Lorenzis G, Cordero-Bueso G, Setati ME, Vigentini I.   +13 more
europepmc   +1 more source

Precision medicine in paediatrics: Progress and priorities

British Journal of Clinical Pharmacology, EarlyView.
Precision medicine is revolutionizing personalized healthcare, advancing both diagnostics and therapeutics at an unprecedented pace. Reviewing the paediatric applications of pharmacometrics, pharmacogenomics and advanced therapy medicinal products highlights not only the relevance of these exciting innovations to frontline care but also the significant
Nicola Husain, Claire Booth, Joseph F. Standing, Charlotte I. S. Barker   +3 more
wiley   +1 more source

The quantification and epistemology of medicines use and polypharmacy tested in an observational study

British Journal of Clinical Pharmacology, EarlyView.
Definitions of ‘medicines use’ and ‘polypharmacy’ may refer to all medicines, regular long‐term medicines or another subset. Valid definitions of medicines use should incorporate type of use (long term, short course and as needed [PRN]), changes in use (start, stop and dose change) and a description of temporal examination (cross‐sectional or ...
Lorna Pairman, Paul Chin, Matthew Doogue
wiley   +1 more source

Cerebrospinal fluid CEFA composition is enriched in saturated fatty acids and it is altered in Alzheimer's disease. [PDF]

J Lipid Res
Pavanello C, Ossoli A, Comi C, Turri M, Tremolizzo L, Conti E, D'Incecco P, Barbiroli A, Parini P, Mitro N, Caruso D, Sierri G, Re F, Chinello C, Fumagalli C, Magni F, Fernandes K, Calabresi L.   +17 more
europepmc   +1 more source

Milano remisión de V. cola de milano.

, 2011
[ES] Definición del término Milano remisión de V. cola de milano. en el diccionario Dicter.
openaire   +1 more source