Results 31 to 40 of about 816,058 (304)
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane +43 more
wiley +1 more source
Finanziarizzazione e mercati urbani in chiave di low geopolitics: considerazioni sul caso Milano
Financialization and Urban Markets through the Lens of Low Geopolitics: Reflections on the Case of Milan The financialization of real estate has reshaped global financial geographies, clustering investments in major cities following low geopolitics ...
Alberto Bortolotti +1 more
doaj +1 more source
A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source
Il saggio esplora la diffusione del nome Giovanni a Milano e nel suo contado tra i secoli XI e XV, mostrando come l’affermazione di questo nome in città sia stata molto successiva a quella nei villaggi rurali.
Federico Del Tredici
doaj +1 more source
Natural born pedagogy. Approcci filosofici e sperimentali alla pedagogia digitale
Review of the book E. Gola & G. Piredda (2016). Natural born Pedagogy. Approcci filosofici e sperimentali alla pedagogia digitale. Milano, IT: Guerini Scientifica Milano, IT:
Fabrizio Ravicchio
doaj +1 more source
Il testo ripercorre il lungo rapporto fra Federico Zeri e la città di Milano, esaminando in particolare quello con i colleghi, i collezionisti, gli antiquari, i ...
Andrea Bacchi
core
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold +12 more
wiley +1 more source
In this work, the influence of native starter cultures on the microbiological, physicochemical and sensorial characteristics of Milano salami type was studied.
Ângela Maria Fiorentini +4 more
doaj +1 more source
Safety and Tolerability of Givinostat: Evidence From Real‐World and Clinical Practice
ABSTRACT Objective The aim of our study was to establish the prevalence of adverse events in a real‐world setting in boys living with Duchenne muscular dystrophy (DMD) treated with givinostat as part of an Expanded Access Program (EAP) in Italy. Methods The cohort included 90 ambulant boys, with age when treatment started between 6 and 23 years (mean ...
Marika Pane +19 more
wiley +1 more source
ABSTRACT Background Collaterals are crucial factors that influence the infarct growth rate (IGR). We aimed to determine whether a comprehensive multimodal collateral score (MCS), incorporating collateral assessment at the arterial, tissue, and venous levels, is associated with functional independence and provides incremental prognostic value over ...
Giorgio Busto +12 more
wiley +1 more source

