Results 221 to 230 of about 828,815 (378)

Antibody‐Empowered Nanomedicine for Precise Biomedical Applications

Advanced Science, EarlyView.
This review explores strategies for functionalizing nanoparticles with antibodies to construct antibody‐empowered nanomedicine. It discusses the classification of these nanomedicines based on antibody structure, with a specific focus on their biomedical applications in diagnostics, bioimaging, and therapeutics for various diseases.
Chen Chen, Xinglin Chen, Zhenhao Gao, Meng Sun, Yaozong Yu, Fang Lv, Qiujun Wang, Jinfeng Zhang   +7 more
wiley   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

Vascular biomarkers and ApoE4 expression in mild cognitive impairment and Alzheimer’s disease

, 2018
Diana C. Oviedo, Héctor Lezcano, Ámbar Pérez-Lao, Alcibiades E. Villarreal, María B. Carreira, Baltasar Isaza, Lavinia Wesley, Shantal Grajales, Sara Gutiérrez Fernández, Ana Frank, Gabrielle B. Britton, Gabrielle B. Britton, 2 Facultad de Medicina, Universidad de Panamá, Panamá, 3 Centro de Neurociencias y Unidad de Investigación Clínica, Instituto de Investigaciones Científicas y Servicios de Alta Tecnología (INDICASAT AIP), Panamá   +13 more
openalex   +2 more sources

The diagnosis and management of mild cognitive impairment: a clinical review.

Journal of the American Medical Association (JAMA), 2014
K. Langa, D. Levine
semanticscholar   +1 more source

Compensatory Interplay Between Clarin‐1 and Clarin‐2 Deafness‐Associated Proteins Governs Phenotypic Variability in Hearing

Advanced Science, EarlyView.
Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling, Aïda Yakhlef Sanchez, Nicolas Thelen, Müge Senarisoy, Maria Hogg, Steven Condamine, Andrea Lelli, Emilia Wysocka, Pranav Patni, Sandrine Vitry, Kerem Yasin Yildizhan, Sébastien Le Gal, Sylvie Nouaille, Michael R. Bowl, Marc Thiry, Didier Dulon, Sedigheh Delmaghani, Aziz El‐Amraoui   +17 more
wiley   +1 more source

The Clinical Significance of Evoked Potentials in the Diagnosis of Mild Cognitive Impairment and Dementia Syndromes - A New Perspective

Wojciech Derkowski
openalex   +1 more source

[O5–07–05]: LACUNAR INFARCTS: A KEY NEUROPATHOLOGICAL FEATURE IN MILD COGNITIVE IMPAIRMENT [PDF]

, 2017
Renata Elaine Paraízo Leite, Mariana Molina, Roberta Diehl Rodriguez, Lea T. Grinberg, Cláudia Kimie Suemoto, Renata Eloah de Lucena Ferretti‐Rebustini, José M. Farfel, Carlos Augusto Pasqualucci, Wilson Jacob Filho, Ricardo Nitríni   +9 more
openalex   +1 more source

AI‐Assisted Bioelectronics for Personalized Health Management

Advanced Electronic Materials, EarlyView.
Recent advances in artificial intelligence (AI)‐assisted bioelectronics, including materials, device fabrication, working mechanisms, AI‐hardware integration, and proof‐of‐concept applications in digital health management, are summarized. The emergence of AI‐assisted bioelectronic systems and potential solutions to existing challenges are discussed ...
Huiwen Xiong, Changhao Dai, Xuting Chen, Jilie Kong, Dacheng Wei, Xueen Fang, Wenhao Weng   +6 more
wiley   +1 more source

Mild cognitive impairment: why bother?

Annals of General Psychiatry, 2008
Gold Gabriel
doaj   +1 more source

Association Between Motor Task Performance and Hippocampal Atrophy Across Cognitively Unimpaired, Amnestic Mild Cognitive Impairment, and Alzheimer’s Disease Individuals

, 2021
Sydney Y. Schaefer, Michael Malek-Ahmadi, Andrew Hooyman, Jace B. King, Kevin Duff   +4 more
openalex   +2 more sources