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Mild cognitive impairment: Believe it or not?
International Review of Psychiatry, 2008Mild cognitive impairment (MCI) was previously defined as a transitional state that can precede dementia, but the condition and the rates of conversion remain controversial. MCI is now the focus of natural history studies, along with Alzheimer's disease (AD) prevention.
Fernando E. Taragano +3 more
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Mild Cognitive Impairment in Geriatrics
Clinics in Geriatric Medicine, 2018Mild cognitive impairment remains a clinical diagnosis, aided by history, neurologic examination, screening mental status examination, and secondary testing. It can be difficult to distinguish from normal aging without understanding a patient's prior level of intellectual function and new complaint.
Eric G. Tangalos, Ronald C. Petersen
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Mild Cognitive Impairment and Dementia
Annual Review of Clinical Psychology, 2006Mild cognitive impairment (MCI) is a clinical syndrome thought to represent the transition between normal function and dementia. This review describes data that support the existence of such a transitional phase, outlines the heterogeneity of MCI and how that has influenced the evolving concept of MCI, and discusses the impact of heterogeneity on ...
Marilyn Albert, Deborah Blacker
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Leukoaraiosis with mild cognitive impairment [PDF]
Neurological Research, 2015 As the ageing population continues to increase, the prevalence of age-related cognitive impairment has been on the rise. Mild cognitive impairment (MCI) is now widely recognised as the early stage of dementia. Mild cognitive impairment is closely associated with cerebral white matter lesions (WMLs), specifically in the case of leukoaraiosis (LA).
Chuanqiang Qu +4 more
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The economics of mild cognitive impairment
Alzheimer's & Dementia, 2012Individuals with amnestic mild cognitive impairment (MCI) are at elevated risk of developing Alzheimer's disease (AD). Although the economic burden of AD itself is well recognized, little is known about the direct and indirect costs associated with MCI before the onset of AD.
Peter J. Neumann, Pei-Jung Lin
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Neuropathology of mild cognitive impairment
Neuropathology, 2007We aim to investigate the pathological background of mild cognitive impairment (MCI). The most recent 545 cases from the Brain Bank for Aging Research (BBAR) were studied, with a mean age of 80.7 years and male : female ratio of 324 : 221. Cases with clinical dementia rating scale (CDR) 0.5 were retrieved as the best substitute of MCI.
Yuko Saito, Shigeo Murayama
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Frontotemporal mild cognitive impairment
Journal of Alzheimer's Disease, 2004Mild Cognitive Impairment appears to be a heterogeneous clinical entity comprising patients in the initial phases of distinct neurological disorders. Since frontotemporal dementia (FTD) is a relatively common neurodegenerative disease with an insidious onset, it might be possible to detect the patients in the initial phases of the disorder, before ...
Alexandre de Mendonça +3 more
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Discussing Mild Cognitive Impairment
Focus, 2021Dr. Purganan reports that her spouse has served on an advisory board for Dova Pharmaceuticals and Targeted Oncology, has served as a speaker for the Chronic Liver Disease Foundation/Focus Medical Communications, has received research funding from Arrowhead Pharmaceuticals, and has received sponsored travel for research support from Arrowhead ...
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Donepezil for mild cognitive impairment
Cochrane Database of Systematic Reviews, 2006Problems with memory which do not meet the diagnostic criteria for dementia, usually called mild cognitive impairment (MCI), can be the first sign of an impending dementia, particularly Alzheimer's disease (AD). There is no consensus on a definition or diagnostic criteria for MCI, and MCI remains a vague term and those so described are a heterogeneous ...
Leon Flicker, Jacqueline Birks
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Hypertension and Mild Cognitive Impairment
Current Hypertension Reports, 2012The brain is an early target for organ damage due to high blood pressure. Hypertension is the major modifiable risk factor for stroke and small vessel disease. It has been suggested that cerebral microvascular disease contributes to vascular cognitive impairment.
Antonio Coca +3 more
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