Results 131 to 140 of about 1,254,613 (316)

A Hepatocyte‐to‐Stellate Cell Axis Couples Alternate‐Day Fasting to Liver Fibrosis Resolution via ATG7 S‐Nitrosylation

open access: yesAdvanced Science, EarlyView.
Alternate‐day fasting suppresses mitochondrial complex II assembly via SDHAF4 to upregulate hepatocyte eNOS. The resulting nitric oxide S‐nitrosylates ATG7 at C184 in hepatic stellate cells, restraining autophagic flux and preventing their profibrotic activation.
Xueqiang Wang   +17 more
wiley   +1 more source

James Naughton Interview

open access: yes, 2006
Mr. James Naughton served for three years in the United States Marine Corps. Much of that time was spent in the hospital due to serious injuries received as a result of combat action during the Battle of Iwo Jima in 1945. Mr.
Naughton, James B.
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Low‐Intensity Ultrasound‐Triggered Microbubble Cavitation Attenuates Diabetic Kidney Injury Partially by Reversing Endothelial Dysfunction

open access: yesAdvanced Science, EarlyView.
Non‐invasive low‐intensity pulsed ultrasound ‐triggered cavitation of clinically approved diagnostic‐grade microbubbles delivers favorable mechanical stimuli to renal microvasculature. This intervention restores renal microvascular homeostasis, alleviates DKD‐associated histological and functional damage, and suppresses inflammatory and fibrotic ...
Yubo Lai   +8 more
wiley   +1 more source

Ronald Ray Interview

open access: yes, 2006
Ronald Ray (COL USMCR, RET) was born in Kentucky in 1942 and graduated from Centre College and the University of Louisville School of Law. He was commissioned 2nd Lieutenant in the United States Marine Corps Reserve in 1964 and spent the next five years ...
Ray, Ronald
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Neonatal Sevoflurane Exposure Induces Long‐Term Cognitive Impairment via Epigenetically Mediated MMP9 Activation and Perineuronal Net Disruption in the Hippocampal CA2

open access: yesAdvanced Science, EarlyView.
Hippocampal CA2 perineuronal nets ensheathing excitatory pyramidal neurons are selectively vulnerable to repeated neonatal sevoflurane exposure. Epigenetic upregulation of MMP9 via reduced H3K27me3 disrupts PNN integrity, impairs BDNF–TrkB signaling, and causes synaptic protein loss and dendritic spine deficits, leading to persistent social and spatial
Lirong Liang   +11 more
wiley   +1 more source

William D. Badgett Interview

open access: yes, 2005
William D. Badgett graduated from VMI in 1953 and served in the USAF as a 1st Lieutenant from November 1953 to July 1955; he was stationed in Korea from July 1954 – 1955.
Badgett, William D.
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Immunomagnetic‐MXene Bifunctional Probes for Ultrasensitive and Specific Terahertz Metasensing of Tumor‐Derived Exosomes

open access: yesAdvanced Science, EarlyView.
An immunomagnetic‐MXene bifunctional probe integrated with THz metamaterials enables ultrasensitive and specific detection of pancreatic cancer‐derived exosomes. Dual biomarker recognition ensures high specificity, while MXene signal amplification achieves a detection limit of 647 particles mL−1.
Weidong Jin   +8 more
wiley   +1 more source

Leonard Lewane Interview

open access: yes, 2003
Lewane was commissioned in the United States Army following his graduation from VMI in 1950 and rose to the rank of Colonel before retiring in 1974. This interview covers his entire military career and includes extensive information about his service in ...
Lewane, Leonard L.
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Orthogonal Light‐ and Enzyme‐Triggered and‐Gate Prodrugs for Senolytic Therapy

open access: yesAdvanced Science, EarlyView.
An orthogonal AND‐gate prodrug platform combines 390 nm near‐UV photocleavage with SA‐β‐gal activation to control payload release in senescent cells. Its modular architecture enables 4‐MU fluorescence, doxorubicin‐mediated cytotoxicity, and ARV‐771‐driven BRD4 degradation, supporting stimulus‐controlled senolytic design in cellular and organoid models.
Mengyang Chang   +12 more
wiley   +1 more source

Superintendent George R. E. Shell with Austrian Military Academy cadet, June 1963

open access: yes, 1963
Cadet Friedrich Dialer from the Austrian National Military Academy in Weiner Neustadt, Austria visits VMI in June of 1963 for the ROTC Summer Session. Gen.

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