Results 41 to 50 of about 1,996,878 (265)
Advanced Science, EarlyView.Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang +10 more
wiley +1 more source
Development of a mobile wind power plant for power supply of the troops
Шәкәрім университетінің хабаршысы: Техника ғылымдар, 2023 The scientific article was published as part of the implementation of the scientific project of grant funding for 2022-2024 IRN № АР148039/0222 «Scientific and technical substantiation of the parameters and development of a wind power plant for the ...
B. B. Каbulov, E. K. Аdilbekov
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Macrophage PABPC4‐SPP1 Axis Orchestrates Immunosuppression in Colorectal Cancer
Advanced Science, EarlyView.In the CRC microenvironment, macrophage PABPC4 binds to the 3′UTR of SPP1 mRNA to stabilize its expression, thereby sustaining M2‐like immunosuppressive macrophage polarization. Concurrently, this axis suppresses CD8+ T cell effector functions via CD44 signaling, collectively fostering an immunosuppressive niche that drives tumor progression.
Meng Wang +14 more
wiley +1 more source
Kalmykia on the Defense of the Fatherland
Oriental Studies, 2018 Owing to patriotism, solidarity of the people, scientific and economic potential, the Soviet Union not only withstood the attack of Nazi Germany but crushed the Nazis seventy years ago. In order to protect the freedom and independence of the country, the
K. Maksimov
doaj
Advanced Science, EarlyView.Guided by spatial transcriptomics and clinical validation, a threaded microneedle platform enables precise layer‐specific delivery across the dermis and subcutaneous tissue. By addressing distinct pathogenic remodeling in different skin layers, this strategy coordinates compartment‐specific intervention, restores tissue architecture, and offers a ...
Fangzhou Xie +14 more
wiley +1 more source
Advanced Science, EarlyView.Pathological tissue rigidity mechanoprimes microglia by enhancing actin cytoskeleton–nucleus coupling and chromatin opening at rigidity‐responsive cis‐regulatory elements (mechanoCREs). Subsequent NF‐κB/p65 signaling converges on this permissive regulatory state to amplify inflammatory gene expression and microglial activation.
Yu Xuan Meng +15 more
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Parasites & Vectors, 2021 Background Colombia’s National Army is one of the largest military institutions in the country based on the number of serving members and its presence throughout the country.
Omar Cantillo-Barraza +10 more
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Advanced Science, EarlyView.Alternate‐day fasting suppresses mitochondrial complex II assembly via SDHAF4 to upregulate hepatocyte eNOS. The resulting nitric oxide S‐nitrosylates ATG7 at C184 in hepatic stellate cells, restraining autophagic flux and preventing their profibrotic activation.
Xueqiang Wang +17 more
wiley +1 more source
Bulletin of Kharkiv National University of Internal AffairsThe scientific research is devoted to establishing the peculiarities of interaction between various authorities to ensure the provision of rehabilitation assistance to military personnel in Ukraine.
O. A. Ivakhnenko
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Advanced Science, EarlyView.Hippocampal CA2 perineuronal nets ensheathing excitatory pyramidal neurons are selectively vulnerable to repeated neonatal sevoflurane exposure. Epigenetic upregulation of MMP9 via reduced H3K27me3 disrupts PNN integrity, impairs BDNF–TrkB signaling, and causes synaptic protein loss and dendritic spine deficits, leading to persistent social and spatial
Lirong Liang +11 more
wiley +1 more source