Results 101 to 110 of about 167,026 (327)

Lactobacillus johnsonii Generates Cyclo(pro‐trp) and Promotes Intestinal Ca2+ Absorption to Alleviate CKD–SHPT

Advanced Science, EarlyView.
The mechanism map of how L.johnsonii generates cyclo(pro‐trp) to alleviate CKD–SHPT by promoting the expression of CaSR and TRPV4 in IECs, enhancing Ca2+ absorption, and negatively feedback inhibiting iPTH secretion. Abstract Patients with chronic kidney disease (CKD) are at a high risk of developing secondary hyperparathyroidism (SHPT), which may ...
Xiong Zeng, Lihua Sun, Huichao Xie, Shenhai Gong, Caibao Lu, Zhongwei Xu, Haidi Guan, Ben Han, Wei Wang, Zhengmin Zhang, Jieying Zhou, Shuai Wang, Yihui Chen, Weidong Xiao   +13 more
wiley   +1 more source

On the Evaluation of Military Simulations: Towards A Taxonomy of Assessment Criteria [PDF]

Military Communications and Information Systems 2015, 2020
In the area of military simulations, a multitude of different approaches is available. Close Combat Tactical Trainer, Joint Tactical Combat Training System, Battle Force Tactical Training or Warfighter's Simulation 2000 are just some examples within the history of the large DoD Development Program in Modelling and Simulation, representing just a small ...
arxiv  

The Latest Advances in Mechanically Robust Self‐Healing Polyurea Based on Dynamic Chemistry

Advanced Science, EarlyView.
Solving the contradiction between strength, toughness, and self‐healing properties is extremely important to realize the breakthrough of polyurea applications. This review summarizes and discusses common strategies for the preparation of high‐performance and self‐healing polyurea materials based on dynamic chemistry, providing molecular‐level insights ...
Yujia Hao, Guangming Zhu
wiley   +1 more source

Effects of acute high‐altitude exposure on working memory: A functional near‐infrared spectroscopy study

Brain and Behavior, Volume 12, Issue 12, December 2022., 2022
The current study adopted an experimental paradigm of digital span to evaluate acute high‐altitude exposure impairment on working memory. The subjects showed obvious physiological adaptation mechanism at acute altitude. The results of hemodynamic response confirmed the important role of left DLPFC in the process of working memory, revealed abnormal ...
Li Wang, Linqiong Sang, Yu Cui, Pengyue Li, Liang Qiao, Qiannan Wang, Wenqi Zhao, Qiu Hu, Najing Zhang, Ye Zhang, Mingguo Qiu, Jian Chen   +11 more
wiley   +1 more source

Silicon Enhances Functional Mitochondrial Transfer to Improve Neurovascularization in Diabetic Bone Regeneration

Advanced Science, EarlyView.
These findings reveal that silicon exerts strong protective effects in diabetic bone defect models by selectively promoting Drp1‐Mff activity. Silicon facilitates precise regulation of mitochondrial dynamics to enable functional mitochondrial transfer.
Yu‐Xuan Ma, Chen Lei, Tao Ye, Qian‐Qian Wan, Kai‐Yan Wang, Yi‐Na Zhu, Ling Li, Xu‐Fang Liu, Long‐Zhang Niu, Franklin R. Tay, Zhao Mu, Kai Jiao, Li‐Na Niu   +12 more
wiley   +1 more source

The relationship between dietary patterns and aggressive behavior in adolescent girls: A cross‐sectional study

Brain and Behavior, Volume 12, Issue 12, December 2022., 2022
Abstract Background There are few studies about the relationship between dietary patterns and aggression. The aim of this study was to assess the relationship between the main dietary patterns and aggression scores among adolescent girls in Iran. Methods This cross‐sectional study was conducted on 670 adolescent girls.
Mahsa Malekahmadi, Sayyed Saeid Khayyatzadeh, Javad Heshmati, Shadia Hamoud Alshahrani, Nikzad Oraee, Gordon A. Ferns, Safieh Firouzi, Naseh Pahlavani, Majid Ghayour‐Mobarhan   +8 more
wiley   +1 more source

The challenges of military medical education and training for physicians and nurses in the Nordic countries - an interview study

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2017
Background Development and use of e-learning has not taken place to the same extent in military medicine in the Nordic countries. The aim was to explore the similarities and differences in education and training in military medicine for health ...
Linda Sonesson, Kenneth Boffard, Lars Lundberg, Martin Rydmark, Klas Karlgren   +4 more
doaj   +1 more source

Mannose‐Glycated Metal‐Phenolic Microcapsules Orchestrate Phenotype Switch of Macrophages for Boosting Tumor Immunotherapy

Advanced Science, EarlyView.
Immunomodulatory metal‐phenolic microcapsules (mMPMs) is developed in this study that leverages dopamine‐modified hyaluronic acid and FeIII assemble on mannose‐glycated bovine serum albumin microbubbles. mMPMs effectively promote macrophage internalization and M1 polarization, enhancing pro‐inflammatory responses.
Xin Tan, Renwang Sheng, Weikun Li, Yinghua Tao, Zonghao Liu, Ning Yang, Syeda Safia Hashmi, Feiling Feng, Fangzhou Liu, Liqin Ge   +9 more
wiley   +1 more source

Targeted Delivery of α‐ketoglutarate to Macrophages in Bone: A Novel Therapeutic Strategy for Improving Fracture Healing in Type 2 Diabetes

Advanced Science, EarlyView.
The study reveals that glutaminolysis in macrophages is inhibited under type 2 diabetes mellitus (T2DM) conditions, which impedes fracture healing by reducing bone morphogenetic protein 2 (BMP2) production through increased cytosine methylation on the promoter.
Jing Wang, Jiahao Cao, Siqi Zhang, Hongli Chen, Xuebing Yu, Xinli Wang, Tianji Wang, Wei Cao, Wengang Dong, Xinsen Lin, Jia Li, Wei Lei, Yafei Feng   +12 more
wiley   +1 more source

Tetrahedral Nitrogen Atoms Arrangement in A‐Site Cations: A New Approach for Regulating Sensitivity and Energy of Perovskite Energetic Materials

Advanced Science, EarlyView.
The urotropine is selected as the A‐site cation in PEMs, and four urotropine‐based PEMs ([C6H14N4][M(ClO4)3]) are successfully prepared. Compared with the cubic PEMs, the crystal structure of the urotropine‐based PEMs has an expansion along the c‐axis.
Shiyong Chen, Yuan Gao, Cheng Dong, Lixiao Shen, Yinning Zeng, Peng Bao, Yan Li, Zhenxin Yi, Houhe Chen, Shunguan Zhu, Lin Zhang   +10 more
wiley   +1 more source