Results 161 to 170 of about 665,581 (347)

Adeno‐associated virus serotype 2 capsid variants for improved liver‐directed gene therapy

open access: yesHepatology, EarlyView., 2022
Abstract Background and Aims Current liver‐directed gene therapies look for adeno‐associated virus (AAV) vectors with improved efficacy. With this background, capsid engineering is explored. Whereas shuffled capsid library screenings have resulted in potent liver targeting variants with one first vector in human clinical trials, modifying natural ...
Nadja Meumann   +25 more
wiley   +1 more source

Minimalist Footwear Acutely Alters Running Kinematics in Runners With Medial Tibial Stress Syndrome

open access: yesArthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To assess immediate biomechanical changes in runners with medial tibial stress syndrome (MTSS) when transitioning from standard to minimalist running shoes. Methods Active runners diagnosed with MTSS ran on a treadmill at 10 km/h using standard and minimalist running shoes. Hip, knee, and ankle joint kinematics were captured using a 16‐infrared‐
Quyet Thang Nguyen   +6 more
wiley   +1 more source

AIF1+CSF1R+ MSCs, induced by TNF‐α, act to generate an inflammatory microenvironment and promote hepatocarcinogenesis

open access: yesHepatology, EarlyView., 2022
Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong   +9 more
wiley   +1 more source

Cardiopulmonary function in special operations forces compared to conventional infantry soldiers

open access: yesExperimental Physiology
Fitness is essential to military personnel in general, especially in the special operations forces (SOF), where the demanding tasks require a high level of physical fitness and mental robustness.
Rasmus Syberg Rasmussen   +9 more
doaj   +1 more source

Arthroscopic Posterior Labral Repair in Professional Contact Athletes Restores Shoulder Stability and Enables Successful Return to Pre‐injury Competition

open access: yesArthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To evaluate return‐to‐competition rates, posterior shoulder instability recurrences, and revision surgeries following arthroscopic posterior labral repair in this elite cohort. Methods A retrospective review of prospectively collected data included professional contact athletes undergoing primary arthroscopic posterior labral repair by a single
Ayham Jaber   +6 more
wiley   +1 more source

Preoperative Resilience Does Not Predict Functional Outcomes After Rotator Cuff Repair: A Systematic Review

open access: yesArthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To determine whether preoperative or concurrent resilience is related to postoperative functional outcomes after arthroscopic rotator cuff repair (aRCR). Methods A literature search was conducted from PubMed, SportDiscus, and OVID Medline databases to identify studies evaluating the effect of preoperative resilience on postoperative outcomes in
Paxton Sweeney   +6 more
wiley   +1 more source

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