Results 61 to 70 of about 665,581 (347)

Nutraceutical-based integrative medicine: adopting a mediterranean diet pyramid for attaining healthy ageing in veterans with disabilities [PDF]

open access: yes, 2018
Veterans with disability represent a big burden worldwide and often require long-term rehabilitation. Unhealthy dietary and lifestyle habits, including smoke and alcohol abuse, are common in veterans.
Aiello, Paola   +9 more
core   +1 more source

SMAD4 Palmitoylation Drives a Metabolic‐Transcriptional Circuit to Promote Tumorigenesis and Confers Radiosensitivity in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang   +16 more
wiley   +1 more source

Comparing Levels of Fitness of Police Officers between Two United States Law Enforcement Agencies Journal of Sports Medicine and Physical [PDF]

open access: yes, 2018
BACKGROUND: The general physical task demands of law enforcement may suggest that police Officers are of similar fitness levels across cities, states and countries.OBJECTIVE: To investigate whether fitness levels of police Officers from two different ...
Dawes, James   +7 more
core   +2 more sources

Molecular Glue cc‐885 Inhibits VHL‐Deficient Clear Cell Renal Cell Carcinoma via ETS1 Degradation

open access: yesAdvanced Science, EarlyView.
VHL‐deficient kidney cancer lacks effective treatments. This study reveals that the molecular glue degrader cc‐885 hijacks the cellular recycling system to selectively destroy the oncogenic protein ETS1, effectively killing VHL‐mutant tumors. Combining CC‐885 with the approved drug belzutifan achieves powerful synergy, offering a promising new ...
Taowei Yang   +15 more
wiley   +1 more source

Contre les « ennemis invisibles »

open access: yesHistoire, Médecine et Santé, 2016
The first German institute for tropical medicine—the Institut für Schiffs- und Tropenkrankheiten—was created in 1900. A few years later, about 15’000 troops departed from Hamburg to fight in German South-West Africa (modern-day Namibia).
Sílvio Marcus de Souza Correa
doaj   +1 more source

Enzymatic DNA Reaction Networks for Orchestrating Stimuli‐Dependent Temporal Molecular Pulse

open access: yesAdvanced Science, EarlyView.
We present an enzymatic DNA reaction network (EDRN) that encodes nucleic‐acid targets in time, converting inputs into a universal strand and then into programmable transient fluorescence pulses. With time‐color multiplexing, EDRN enables single‐tube high‐plex nucleic acid detection and shows strong agreement with clinical sequencing across 32 specimens.
Jiayu Yang   +7 more
wiley   +1 more source

Comparative analysis of military medical personnel training in Russia and Europe in the 18–19th centuries

open access: yesСеченовский вестник, 2016
The article discusses the history of military medical training in Russia and Western Europe in XVIII–XIX centuries. The leading trend in military medical training in all compared countries was the introduction of militarymedical disciplines: military ...
I. M. Chizh, I. V. Karpenko
doaj  

Multidrug-resistant Tuberculosis in Military Recruits

open access: yesEmerging Infectious Diseases, 2006
We conducted a tuberculosis contact investigation for a female military recruit with an unreported history of multidrug-resistant tuberculosis (MDRTB) and subsequent recurrence.
Grace Freier   +7 more
doaj   +1 more source

Healing a Broken System: Veterans and the War on Drugs [PDF]

open access: yes, 2012
This report examines the plight of returning veterans who struggle with incarceration and psychological wounds of war such as addiction and post-traumatic stress disorder -- and suggests reforms that could improve the health and preserve the freedom of ...

core  

Targeting Supramolecular Active Complexes of Nav1.7/Nav1.8 to Relieve Chronic Neuropathic Pain

open access: yesAdvanced Science, EarlyView.
In mice and patients with severe chronic neuropathic pain (NP), Nav1.7, Nav1.8, TrkB, and five cytoskeletal proteins form supramolecular active complexes (SMACs) with polygonal lattice structures as noxious signal amplifiers in dorsal root ganglion (DRG) neurons.
Liting Sun   +27 more
wiley   +1 more source

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