Results 141 to 150 of about 1,156,956 (356)
Post‐Translational Modified Neoantigens in Autoimmune Diseases: Challenges of Immune Tolerance
Advanced Science, EarlyView.Autoimmune diseases have a high incidence and disability rate. The pathogenesis of autoimmune diseases involves the interaction among genetic factors, environmental factors, and immune disorders. The post‐translational modified neoantigens are the key nodal of these three factors. And these post‐translational modified neoantigens, after being presented
Yue Zhai +5 more
wiley +1 more source
Some Personal Recollections of Army Operations Research on Radar in World War II [PDF]
, 2012 Operational Research had its origin at the beginning of the Second World War, and made important early contributions to many aspects of the Air Defence of Great Britain, an activity of monumental significance in the war.
Lindsey, George
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Advanced Science, EarlyView.This study reveals that the glycolytic enzyme HK2 mediates hypoxia‐induced astrocytic exosome biogenesis by directly phosphorylating nSMase1. These astrocytic exosomes impair brain endothelial tight junctions. Astrocyte‐specific knockdown of HK2 reduces exosome release and alleviates brain injury after MCAO.
Chen Chen +12 more
wiley +1 more source
IX. A memoir on the best method of measuring time at sea, which obtained the double prize adjudged by the royal Academy of Sciences; containing the description of the longitude watch presented to his majesty the 5th of August 1766. Translated from the French by Mr. T. S. E
Malini Roy
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UV‐Triggered Cascading Degradation of Silicone Elastomer via Self‐Fluoride Amplification
Advanced Science, EarlyView.UV‐triggered degradable materials offer proficient control of functional lifetime, while having issues with trigger efficiency. This work enhances the UV‐triggered degradation mechanism of silicone elastomer by introducing the UV‐initiated synergetic fluoride self‐amplification. The silicone composite shows excellent mechanical properties and on‐demand
Yoon‐Nam Kim +5 more
wiley +1 more source
FIELD TRAINING OF STUDENTS AT THE FACULTY OF MILITARY HEALTH SCIENCES, UNIVERSITY OF DEFENCE [PDF]
, 2017 Milan Růžička +5 more
openalex +1 more source
Advanced Science, EarlyView.Novel quaternary ammonium salt‐linked STING agonist ADC demonstrates high potency, stability, enhanced solubility, and reduced off‐target toxicity, potently activating the STING pathway in the tumor microenvironment through the synergistic action of the Fab and Fc regions of antibodies (activity switch‐on) while exhibiting ≈20 fold lower activity in ...
Yu Long +17 more
wiley +1 more source
, 1948 This thesis is a process oriented case-study. The studied case is a interactiondesignassignment of a databasevisualisation and the process. The goalis to do this according to the ways of a screenwriter.When the computers spread from the military and ...
Klasson, Sofia
core +1 more source
Advanced Science, EarlyView.Gasdermin D (GSDMD) does not only reduce pancreatic enzyme synthesis but also induces pancreatic acinar cells to express mucin 1 (MUC1), which forms a barrier to prevent digestive enzyme‐mediated digestion. However, GSDMD can promote the secretion of inflammatory cytokines by macrophages and aggravate pancreatic histological injury by expanding ...
Chaoxu Liu +10 more
wiley +1 more source