Results 201 to 210 of about 1,156,956 (356)

Bispecific Nanosystems Enable Multieffector Immune Cell Retargeting for Hematologic Malignancy Therapy

open access: yesAdvanced Science, EarlyView.
B‐cell lymphomas are aggressive malignancies with limited treatment options. A bispecific nanosystem (biHSNPs) is developed, leveraging silica nanoplatforms to conjugate antibodies targeting immune effector cells and B‐cell antigens. biHSNPs form artificial immunological synapses, activating cytotoxic responses and suppressing tumor proliferation. This
Yefeng Shen   +12 more
wiley   +1 more source

Regulating Enzyme Activity via Microaggregates Mediated by Phase Separation

open access: yesAdvanced Science, EarlyView.
An enzyme‐sequestration strategy for combating postoperative pancreatic fistula (POPF) is developed, employing a D‐peptide called DPMD to induce liquid–solid phase separation (LSPS) of pancreatic proteases. This LSPS‐driven microaggregate approach effectively isolates trypsin and chymotrypsin from their substrates, thereby reducing pancreatic fluid ...
Yang Wang   +7 more
wiley   +1 more source

Mixed Lineage Kinase Domain‐Like Protein (MLKL): From Mechanisms to Therapeutic Opportunities

open access: yesAdvanced Science, EarlyView.
The mixed lineage kinase domain‐like protein (MLKL) acts as the executioner in the necroptosis pathway, transitioning from an inactive to active state through phosphorylation, oligomerization, membrane recruitment, and membrane insertion, ultimately forming membrane hotpots.
Lijuan Xu, Chunlin Zhuang
wiley   +1 more source

Call for papers and instructions for authors for the issue 1-2024

open access: yesVojnotehnički Glasnik
The instructions to authors about the article preparation for publication in the Military Technical Courier are based on the Regulations on categorization and ranking of scientific journals of the Ministry of Education, Science and Technological ...
Nebojša N. Gaćeša
doaj  

Emotion Regulation and Coping in Active Military Personnel: A Systematic Review. [PDF]

open access: yesStress Health
Kirkham R   +6 more
europepmc   +1 more source

Bio‐Inspired SA‐FA Bionic Dual Receptor Electronic Skin for Intelligent Gesture and Material Cognition Systems Enhanced by Static‐Dynamic Mutual Interaction

open access: yesAdvanced Science, EarlyView.
In this work, bionic dual receptor (BDR) e‐skin based on the iontronic and triboelectric effects is proposed, inspired by the slow‐adapting and fast‐adapting receptors. Motivated by intelligent software algorithms and high‐speed hardware circuits, the proposed intelligent autonomous material cognition system integrated with the EDB e‐skin can ...
Hao Li   +5 more
wiley   +1 more source

High Electrical Conductivity Induced by Surface Confinement Effect in Heterostructured Multifunctional Nanofiber Composite Films for Low‐Reflection Electromagnetic Interference Shielding

open access: yesAdvanced Science, EarlyView.
Spray‐coated PVA‐co‐PE/AgNW/MXene films achieve 60.2 dB EMI shielding (8–20 GHz) with low reflection (R = 0.13) at 5.4 wt.% loading. The 3D conductive network enhances absorption, while the film offers high strength (18.33 MPa), Joule heating, photothermal conversion, flexibility, and flame resistance.
Dechang Tao   +8 more
wiley   +1 more source

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