Results 91 to 100 of about 782,631 (300)
Advanced Science, EarlyView.This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang +16 more
wiley +1 more source
THE IMPORTANCE OF MILITARY SCIENCES TO ENSURE NATIONAL SURVIVAL IN FUTURE CONFLICTS [PDF]
Annals: Series on Military SciencesThe recognition of the field of military sciences, intelligence and national security as academic sciences is gaining more and more consistency for guaranteeing national security, not only by forming and strengthening the culture of national security ...
Sorin TOPOR
doaj
Molecular Glue cc‐885 Inhibits VHL‐Deficient Clear Cell Renal Cell Carcinoma via ETS1 Degradation
Advanced Science, EarlyView.VHL‐deficient kidney cancer lacks effective treatments. This study reveals that the molecular glue degrader cc‐885 hijacks the cellular recycling system to selectively destroy the oncogenic protein ETS1, effectively killing VHL‐mutant tumors. Combining CC‐885 with the approved drug belzutifan achieves powerful synergy, offering a promising new ...
Taowei Yang +15 more
wiley +1 more source
Revista Brasileira de Ciências do EsporteResumen El objetivo de esta investigación fue realizar un análisis histórico-bibliométrico de los artículos publicados en revistas científicas chilenas del ámbito de las Ciencias del Deporte, durante los casi 20 años de gobierno militar.
Cristián Alexis Rubilar-Bernal +1 more
doaj +1 more source
Supplementing curriculum of the military academy for the purpose of providing education for country defence [PDF]
Војно делоThrough content analysis, hypothetical and deductive method and comparative analysis, this paper points to the need of supplementing the curriculum of the Military Academy, with subjects pertaining to humanistic social sciences, as contents of narrower ...
Jevtić Dragan M. +2 more
doaj +1 more source
The professions of science in America: their ambivalent history [PDF]
, 1981 Science started to become professionalized in the United States during the Jackson~an period. A principal aim of professionalization was to secure the goals and standards of research from interference by laymen by the institutionalization of scientific
Kevles, Daniel J.
core
Advanced Science, EarlyView.An entity‐centric foundation model, GloPath, is introduced for comprehensive glomerular lesion assessment from routine renal biopsy images. Trained on over one million glomeruli, the framework enables robust lesion recognition, grading, and cross modality diag nosis, while uncovering large‐scale clinicopathological associations.
Qiming He +28 more
wiley +1 more source
Military science: Empires of reason [PDF]
Nature, 2012 Alison Abbott delves into the legacy of a remarkable Italian scientist–spy and avid collector.
openaire +1 more source
Enzymatic DNA Reaction Networks for Orchestrating Stimuli‐Dependent Temporal Molecular Pulse
Advanced Science, EarlyView.We present an enzymatic DNA reaction network (EDRN) that encodes nucleic‐acid targets in time, converting inputs into a universal strand and then into programmable transient fluorescence pulses. With time‐color multiplexing, EDRN enables single‐tube high‐plex nucleic acid detection and shows strong agreement with clinical sequencing across 32 specimens.
Jiayu Yang +7 more
wiley +1 more source
Вестник Московского Университета. Серия XXV: Международные отношения и мировая политика, 2020 The book under review is a new seminal work by Andrey A. Kokoshin, the 6th Secretary of the Security Council of the Russian Federation and a member of the Russian Academy of Sciences. The monograph explores a wide range of applied and theoretical aspects
V. A. Zolotarev
doaj