Results 31 to 40 of about 38,594 (264)

Molecular Glue cc‐885 Inhibits VHL‐Deficient Clear Cell Renal Cell Carcinoma via ETS1 Degradation

Advanced Science, EarlyView.
VHL‐deficient kidney cancer lacks effective treatments. This study reveals that the molecular glue degrader cc‐885 hijacks the cellular recycling system to selectively destroy the oncogenic protein ETS1, effectively killing VHL‐mutant tumors. Combining CC‐885 with the approved drug belzutifan achieves powerful synergy, offering a promising new ...
Taowei Yang, Qihao Li, Kun Ye, Kezhi Liu, Mi Zhou, Minyu Chen, Lican Liao, Kangbo Huang, Zhu Wang, Qiong Deng, Jieyan Wang, Meiyu Jin, Xu Chen, Hui Liang, Jiaxing Zhang, Junhang Luo   +15 more
wiley   +1 more source

Renal PEComa in a young male: A case report and insights from the literature

Urology Case Reports
Perivascular epithelioid cell tumors (PEComas) are rare mesenchymal neoplasms, commonly found in the uterus and retroperitoneum. Renal PEComas are exceedingly rare, often posing diagnostic challenges due to their resemblance to renal cell carcinoma (RCC)
Rashad Sholan, Rufat Aliyev, Malahat Sultan, Anar Almazkhanli, Savalan Karim, Jalal Gasimov   +5 more
doaj   +1 more source

STUDENTS OF MILITARY CLASSES CONCERNING SELECTED ASPECTS OF POLAND’S NATIONAL SECURITY. AN EMPIRICAL STUDY

Security and Defence Quarterly, 2017
This article examines the opinions of students of military classes concerning aspects of Poland’s national security. The main problem of the study is contained in the following question: How do students of military classes describe selected conditions of
Ilona URYCH
doaj   +1 more source

Political Elite as Key Resource of Military Security in Contemporary Society

Управленческое консультирование, 2020
Justification of the political elite as the key socio-political resource of military security is the purpose of this article. The method of research is structural and functional analysis of mili tary security through the prism of activating its socio ...
M. A. Amurov
doaj   +1 more source

Advances and Perspectives in Graphene‐Based Quantum Dots Enabled Neuromorphic Devices

Advanced Science, EarlyView.
Graphene‐based QDs are zero‐dimensional carbon nanomaterials with pronounced quantum confinement and tunable electronic structures. Herein, we summarize their synthesis strategies and functionalization methods, and highlight their functional roles and operating mechanisms in devices, as well as recent advances in neuromorphic electronics. We anticipate
Yulin Zhen, Wei Zeng, Zherui Zhao, JiYu Zhao, Ziyan Huang, Zhuo Chen, Kui Zhou, Guanglong Ding, Su‐Ting Han, Ye Zhou   +9 more
wiley   +1 more source

Supercritical CO2‐Induced Porous MXene Films for Electromagnetic Interference Shielding and Infrared Stealth

Advanced Science, EarlyView.
The phase transition of supercritical CO2 induces the foaming of dense MXene film without compromise inherent structure of MXene nanosheet. The foamed porous MXene film manifests remarkable EMI shielding and infrared thermal camouflage performances. Moreover, the foaming strategy is broadly adaptable and can be extended to other two‐dimensional films ...
Hui Zhao, Shuai Li, Jiabei He, Tong Gao, Jingfeng Wang, Dongxiao Kan, Wangtu Huo, Lixin Chen   +7 more
wiley   +1 more source

Assessing National and Military Security of Russia: Established Procedure and How to Improve It

Вестник Московского Университета. Серия XXV: Международные отношения и мировая политика, 2020
This paper examines established procedure of assessing national and military security of the Russian Federation and outlines ways how to improve it. The author unveils deficiencies of the current set of indicators for measuring national and military ...
S. P. Belokon’
doaj  

DLT Based Authentication Framework for Industrial IoT Devices

Sensors, 2020
The latest technological progress in the industrial sector has led to a paradigm shift in manufacturing efficiency and operational cost reduction. More often than not, this cost reduction comes at the price of dismissing information security, especially ...
Cristian Lupascu, Alexandru Lupascu, Ion Bica   +2 more
doaj   +1 more source

Seeds of change: The impact of Ethiopia's direct seed marketing approach on smallholders' seed purchases and productivity

American Journal of Agricultural Economics, EarlyView.
Abstract While multiple factors explain low adoption rates of improved varieties by small‐scale farmers in sub‐Saharan Africa, a key supply‐side constraint is the limited availability of seed embodying new traits in the volume, quality, price, and timeliness required by farmers. This constraint is partly attributable to classical failures in the market
Dawit Mekonnen, Gashaw T. Abate, Seid Yimam, Rui Benfica, David J. Spielman, Frank Place   +5 more
wiley   +1 more source

Redistributive land reforms, agricultural productivity, and structural change: New cross‐national evidence

American Journal of Agricultural Economics, EarlyView.
Abstract Large‐scale land reforms constitute a substantial redistribution of wealth and reallocation of agricultural land, which is a major form of asset and production input in developing countries. While land redistribution (from the rich to the poor) remains a highly controversial issue, extensive evidence on its effect is limited.
Devashish Mitra, Abdulaziz B. Shifa, Lan Anh Tong, Mehmet A. Ulubasoglu   +3 more
wiley   +1 more source