Results 31 to 40 of about 39,476 (264)

A Multidimensional Engineering Strategy Reprograms Microglia via Targeted and Sustained‐Release Extracellular Vesicles for Spinal Cord Injury Repair

Advanced Science, EarlyView.
A multifunctional EV‐based nanoplatform (Ang‐TEVs@Gel) was engineered via preconditioning, surface targeting, and ROS‐responsive hydrogel encapsulation to reprogram microglia. This system restored autophagy via miR‐664a‐3p/PIK3CA axis, cleared myelin debris, resolved neuroinflammation, and promoted axon remyelination, ultimately achieving robust motor ...
Wu Xiong, Minhao Liu, Mingming Zheng, Jizhou Jia, Ziyan Zhu, Guang Kong, Jie Liu, Juan Wang, Wenbo Li, Qingyuan Wang, Qian Zhu, Peiran Chan, Tao Qin, Jiayang Wu, Yongjie Zhang, Chunming Tang, Cong Li, Jin Fan   +17 more
wiley   +1 more source

DLT Based Authentication Framework for Industrial IoT Devices

Sensors, 2020
The latest technological progress in the industrial sector has led to a paradigm shift in manufacturing efficiency and operational cost reduction. More often than not, this cost reduction comes at the price of dismissing information security, especially ...
Cristian Lupascu, Alexandru Lupascu, Ion Bica   +2 more
doaj   +1 more source

Entorhinal Astrocyte Transplants Restore Spatial Exploration and Alleviate Amyloid‐Beta Pathology in Alzheimer's Mice

Advanced Science, EarlyView.
Impaired MEC astrocytic Ca2+ signaling is associated with fragmented spatial exploration in AD mice. Region‐specific glial progenitor transplantation generates engrafted astrocytes that are accompanied by improved AQP4 polarization, reduced amyloid‐β‐associated pathology, attenuated neuroinflammation, preserved synaptic integrity, and ameliorated ...
Fengjuan Wu, Jihua Fan, Xiang Zhou, Zhiqi Yang, Mingyue Gong, Mingzhu Huang, Zhenlu Cai, Shaofan Yang, Teng Teng, Chuanyan Yang, Jin Li, Haoyu Wang, Shuangshuang Dai, Chunhai Chen, Xiaowei Chen, Manxia Wang, Kuan Zhang   +16 more
wiley   +1 more source

From Magnetic Fibers to Paper Architectures: A Lightweight Strategy for Robust Low‐Frequency Microwave Absorption

Advanced Science, EarlyView.
A scalable process converts para‐aramid fibers into soft‐magnetic building blocks via micrometer‐thick Fe0.64Ni0.36 (Invar‐type) coatings. Assembled into paper, they form a hierarchical conductive network whose tunable permeability enables thin, lightweight microwave absorption in the low‐frequency (S‐band) regime.
You Wu, Yanlong Li, Haitong Sun, Tao Liu, Kehai Liu, Kaihui Liu, Zhaoxia Sun, Wenbo Ju   +7 more
wiley   +1 more source

Renal PEComa in a young male: A case report and insights from the literature

Urology Case Reports
Perivascular epithelioid cell tumors (PEComas) are rare mesenchymal neoplasms, commonly found in the uterus and retroperitoneum. Renal PEComas are exceedingly rare, often posing diagnostic challenges due to their resemblance to renal cell carcinoma (RCC)
Rashad Sholan, Rufat Aliyev, Malahat Sultan, Anar Almazkhanli, Savalan Karim, Jalal Gasimov   +5 more
doaj   +1 more source

Political Elite as Key Resource of Military Security in Contemporary Society

Управленческое консультирование, 2020
Justification of the political elite as the key socio-political resource of military security is the purpose of this article. The method of research is structural and functional analysis of mili tary security through the prism of activating its socio ...
M. A. Amurov
doaj   +1 more source

Precisely Regulating 2.45 s Pure Blue Room‐Temperature Phosphorescence via Supramolecular Coordination

Advanced Science, EarlyView.
Herein, a pure deep blue room‐temperature phosphorescence (415 nm) with lifetime up to 2.45 s is successfully achieved by a covalently crosslinking purely organic material based on boric acid (BA) and 3,5‐dicarboxyphenylboronic acid (BOP) through a simple dehydration reaction, which can be adjusted precisely by supramolecular coordination with ...
Jun Wang, Xingting Que, Zhiming Chen, Jingsheng Zhang, Wei‐Lei Zhou, Wen‐Wen Xu   +5 more
wiley   +1 more source

Successful Kidney Transplantation in Turner Syndrome: A Case for Feasibility and Favorable Outcomes

Clinical Case Reports
Turner syndrome (TS) leads to various abnormalities, including renal malformations that can progress to end‐stage renal disease (ESRD). Although rarely performed in patients with TS, renal transplantation offers significant benefits over dialysis.
Rashad Sholan, Rufat Aliyev, Nargiz Bakhshaliyeva, Rahman Ismayilov, Anar Almazkhanli, Malahat Sultan   +5 more
doaj   +1 more source

In Vivo engineering of transgenic mice for systemic human neutralizing antibody production against staphylococcal enterotoxin B

Frontiers in Immunology
Transgenic animal bioreactors provide a complementary strategy to traditional mammalian cell culture systems for the production of therapeutic human monoclonal antibodies (mAbs).
Zhiyang Jiang, Zhiyang Jiang, Beichen Jia, Beichen Jia, Naijing Hu, Naijing Hu, Mengmeng Zhang, Mengmeng Zhang, He Xiao, He Xiao, Guojiang Chen, Guojiang Chen, Jijun Yu, Jijun Yu, Xinying Li, Xinying Li, Beifen Shen, Beifen Shen, Jiannan Feng, Jiannan Feng, Jing Wang, Jing Wang   +21 more
doaj   +1 more source

Integrating Reinforcement Learning With Explainable Artificial Intelligence for Real‐Time Clinical Decision Support in Dynamic Healthcare Environments

Advanced Intelligent Systems, EarlyView.
A hybrid Reinforcement Learning–Explainable AI framework integrates SHAP and LIME explanations directly into a Deep Q‐Network inference loop for real‐time ICU decision support. Trained on 18 142 mechanically ventilated stays from the eICU database, the system attains 93.0% decision accuracy, 20% fewer errors than RL alone, and a 91% clinician trust ...
Jannatul Ferdaus Disha, MD Faiaz Zaman Dehan, Kazi Md. Tanvir Anzum   +2 more
wiley   +1 more source