Results 71 to 80 of about 4,285 (216)
ABSTRACT Objective To identify inflammatory analytes in cerebrospinal fluid (CSF) and plasma associated with cognitive decline in cognitively normal (CN) older adults at risk for Alzheimer's disease (AD). Methods In a longitudinal study of 118 CN older adults (65–80 years, 54% APOE ε4, 26% preclinical AD), 1331 CSF and 1501 plasma analytes were ...
Jagan A. Pillai +13 more
wiley +1 more source
Systemic Extracerebral Atherosclerotic Burden and Dementia Risk After Incident Stroke
ABSTRACT Background Stroke survivors are at increased risk of dementia, but clinically accessible markers of risk heterogeneity remain limited. Previous studies have largely examined atherosclerotic disease in individual vascular beds rather than the overall burden of systemic extracerebral atherosclerosis.
Zhexuan Yu +4 more
wiley +1 more source
Personnel Policy Of The Mari Militia in the 60th – 90th of the XX Century: Problems of Continuity
The article analyses the status and problems of continuity in the personnel policy of the Ministry of Internal Affairs of the Mari ASSR from 1961 to 1991. The authors examine the basic forms and methods of ensuring the continuity of militia personnel and
Ivanov V. A., Boyarintseva I. A.
doaj
Efficacy of Fampridine on Refractory Optic Neuritis in Neuromyelitis Optica Spectrum Disorders
ABSTRACT Background Neuromyelitis optica spectrum disorders (NMOSD) usually occur with acute refractory optic neuritis (ON). However, there is a lack of efficacious treatments to improve recovery. Since fampridine has been found to improve the prognosis of multiple sclerosis (MS) and MS‐related ON, it is necessary to explore the efficacy of fampridine ...
Hongxuan Wang +9 more
wiley +1 more source
Passport System Campaign in the Closed Cities of Kuzbass in 1933
In 1933, Kuzbass entered the national passport system project to become one of its leaders in Western Siberia. Modernization proceeded here at an accelerated rate and had a pronounced industrial character.
Natalia N. Ablazhey
doaj +1 more source
A Two‐Stage Plasma Biomarker Algorithm Reduces Amyloid PET Use and the p‐Tau217 Gray Zone
ABSTRACT Objective Plasma p‐Tau217 leaves 30%–50% of patients in an indeterminate “gray zone” often requiring Aβ‐PET. We developed GRAD (Gatekeeper‐Reflex for Alzheimer's Disease), a two‐stage Aβ‐positivity prediction model to improve classification while reserving Aβ‐PET for residual uncertainty.
Harthik Parankusham +7 more
wiley +1 more source
Objective The aim of this study was to test the hypothesis that multijoint osteoarthritis would modify the relation between time and frailty progression, in which more affected joints would lead to larger declines over six years compared to those without osteoarthritis using data from the Canadian Longitudinal Study on Aging.
Carson Halliwell +2 more
wiley +1 more source
The constitutional path of Slovenia towards an independent, sovereign and effective state
The purpose of this article is to explain how the Republic of Slovenia translated the constitutional right of self-determination into independent statehood through a legally structured sequence of constitutional amendments, plebiscitary authorization ...
Tomaž Čas, David Petelin
doaj +1 more source
Objective For cartilage morphology to serve as a scalable endpoint in clinical trials, analyses should be performed automatically without human interaction. To clinically validate artificial intelligence (AI)‐based analysis, we studied cartilage loss from MRI prior to knee replacement.
Felix Eckstein +3 more
wiley +1 more source
The activities of the Ukrainian SSR militia in combating crime in the early 1960s.
The article examines the state of crime in the Ukrainian SSR in 1962–1964 and the range of measures taken by the leadership of the Ministry of Public Order and its subdivisions in regions, cities and districts to counteract it.
V. A. Grechenko
doaj +1 more source

