Results 91 to 100 of about 1,198,612 (297)

Reconfigurable Nucleic Acid Nanoparticles with Therapeutic RNAi Responses to Intracellular Disease Markers

open access: yesAdvanced Functional Materials, EarlyView.
Many known diseases arise from dysregulated gene expression, and differentially expressed genes can serve as biomarkers to distinguish diseased cells from healthy tissues. In this study, reconfigurable nucleic acid nanoparticles (recNANPs) are introduced that can detect overexpressed cancer biomarkers and subsequently release RNAi inducers to silence ...
Yelixza I. Avila   +7 more
wiley   +1 more source

FeDSNP‐Pa Nanoassemblies: A Triple‐Action Therapeutic Strategy Targeting Oxidative Stress, Inflammation, and Pyroptosis for Retinal Ganglion Cell Protection in Glaucoma

open access: yesAdvanced Functional Materials, EarlyView.
FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu   +5 more
wiley   +1 more source

Diversity of Human Milk Oligosaccharides and Effects on Early Life Immune Development

open access: yesFrontiers in Pediatrics, 2018
One of the well-known features of human milk, is the capacity to protect against the risk and impact of neonatal infections, as well as to influence the onset of allergic and metabolic disease manifestations.
Veronica Ayechu-Muruzabal   +8 more
doaj   +1 more source

Antibody‐Programmable Bimetallic Nanozymes for Transcriptional Blockade Therapy in HER2/ER‐Positive Breast Cancer

open access: yesAdvanced Functional Materials, EarlyView.
Zr‐Fe MOF@Ribociclib@Herceptin (ZFRH) efficiently targets/kills Human Epidermal Growth Factor Receptor 2/Estrogen Receptor‐positive (HER2/ER+) breast cancer cells. It combats tumors by: 1) Elevating ROS, altering redox balance; 2) Inhibiting transcription; 3) Inducing pyroptosis.
Hongkun Miao   +8 more
wiley   +1 more source

Corrigendum: Vitamin E concentration in breast milk in different periods of lactation: Meta-analysis

open access: yesFrontiers in Nutrition, 2023
Yuandi Xi   +17 more
doaj   +1 more source

Research Progress of Sensors Technology Based on DNA Walker in Food Safety Detection

open access: yesShipin gongye ke-ji
With the rapid development of DNA nanotechnology, DNA molecules with various structures and functions are used to construct programmable nanomachines with dynamic behaviors.
Siqing SONG   +5 more
doaj   +1 more source

Catalytic TiO2 with Self‐Assembled Monolayer for Highly Sensitive, Selective, and Non‐Invasive Monitoring of Sweat L‐Cysteine

open access: yesAdvanced Functional Materials, EarlyView.
A self‐assembled monolayer of 3‐mercaptopropyltrimethoxysilane (MPTS) molecular receptor and titanium oxide‐modified carbon cloth (MPTS/TiO2/CC) was synthesized for the specific detection of sweat L‐cysteine, which is associated with the precision neutrition, cardiovascular system and neuro system.
Xiangjie Chen   +11 more
wiley   +1 more source

Donation barriers, enablers, patterns and predictors of milk bank donors in the United States and United Kingdom

open access: yesMaternal and Child Nutrition
Pasteurised donor human milk is recommended for very low birthweight infants who do not have access to their mother's milk. Although the use of donor milk continues to increase, little is known about the donation experiences of milk bank donors. We aimed
Bruna Gutierrez dosSantos   +3 more
doaj   +1 more source

Cat‐Vibrissa‐Inspired Biomass Fiber Aerogels for Flexible and Highly Sensitive Sensors in Monitoring Human Sport

open access: yesAdvanced Functional Materials, EarlyView.
Inspired by cat vibrissae, biomimetic biomass PHFs/SA aerogels (BFAs) are developed via precursor‐assisted in situ polymerization and freeze‐synergistic assembly. These ultralight, porous pressure sensors exhibit high sensitivity and excellent durability, enabling pulse detection, handwriting recognition, Morse code transmission, and notably real‐time ...
Dandan Xie   +6 more
wiley   +1 more source

At‐Home Early Diagnosis of Mastitis: Calibration‐Free Analysis of Sodium to Potassium Ratio in Breast Milk

open access: yesAdvanced Functional Materials, EarlyView.
MAMAWEL is introduced as the first calibration‐free potentiometric sensor for at‐home mastitis diagnosis. By measuring the sodium‐to‐potassium ratio in breast milk, the device reliably differentiates between healthy and mastitis‐affected samples with less than 10% error.
Ali Soleimani   +9 more
wiley   +1 more source

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