Results 191 to 200 of about 498,283 (262)

Extracellular Vesicles of Streptococcus anginosus Mediate Gastritis via Epithelial Barrier Disruption and Macrophage‐driven Inflammation

open access: yesAdvanced Science, EarlyView.
Streptococcus anginosus extracellular vesicles (SA‐EVs) accumulate in gastric tissue, disrupt epithelial tight junctions, and induce gastritis characterized by neutrophil infiltration and elevated cytokines (TNF‐α, IL‐6, IL‐17A). Proteomics identifies TMPC and FBP62 as key SA‐EVs virulence factors; their genetic deletion attenuates inflammation ...
Ying Gong   +12 more
wiley   +1 more source

Enhanced bioavailability of a krill oil-based milk thistle extract formulation: <i>in vitro</i> and human studies. [PDF]

open access: yesFood Nutr Res
Engelhart-Jentzsch K   +9 more
europepmc   +1 more source

PTG‐Dependent Glycogen Metabolic Dysfunction Drives Impaired Adipose Browning: A Novel Mechanism Linking PM2.5 to Metabolic Disorders

open access: yesAdvanced Science, EarlyView.
This study provides the first evidence that PM2.5 impairs iWAT browning via PTG‐mediated glycogen metabolism disruption, which is initiated by ADRB3 inhibition and subsequently triggers VEGFB upregulation. It thereby delineates the ADRB3‐PTG‐VEGFB axis as central to PM2.5‐induced metabolic dysfunction and identifies adipose glycogen metabolism as a ...
Limin Wang   +12 more
wiley   +1 more source

From rumen to milk: Dietary polyphenols in dairy cows-A critical review. [PDF]

open access: yesVet Anim Sci
Forte L   +9 more
europepmc   +1 more source

Hepatocyte Mettl3 Deficiency Drives Primary Sclerosing Cholangitis and Liver Fibrosis via Cholangiocyte‐Macrophage Crosstalk

open access: yesAdvanced Science, EarlyView.
Schematic illustration demonstrating that hepatic Mettl3 depletion significantly elevates the secretion of Mif and Csf1. This elevation facilitates Trem2+ macrophage infiltration and triggers cholangiocyte remodeling through the Spp1‐Cd44 interaction, resulting in spontaneous PSC development in vivo.
Wenting Pan   +19 more
wiley   +1 more source

Correction: Cost analysis of establishing and operating the first human milk bank at Da Nang Hospital for women and children in Vietnam: an activity-based costing ingredients study

open access: yesInternational Breastfeeding Journal
Minh V. Hoang   +7 more
doaj   +1 more source

Workflow for the Isolation and Characterisation of Human Milk Extracellular Vesicles (HMEVs) and Their Inflammatory Biomarker Profile. [PDF]

open access: yesJ Extracell Biol
Moreno-Casillas JL   +12 more
europepmc   +1 more source

Disrupting the Formation of YAP Condensates Promotes the Activation of AMPKα to Inhibit the Progression of Primary Liver Cancer

open access: yesAdvanced Science, EarlyView.
This study systematically investigates the function and molecular mechanisms of YAP phase separation in multiple primary liver cancers. These findings provide novel insights into phase separation‐mediated primary liver cancer development and validate targeted disruption of this process as an effective therapeutic strategy for primary liver cancer ...
Shuang‐Zhou Peng   +7 more
wiley   +1 more source

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