Results 201 to 210 of about 466,855 (248)

Nanoparticle‐Mediated CXCL12–CXCR4 Inhibition Reprograms Macrophages and Suppresses Gastric Carcinoma

Advanced Science, EarlyView.
Molecular mechanism study of self‐assembled M2pep‐Cs NPs/Plerixafor nanoparticles in targeting MΦ reprogramming by regulating the CXCL12–CXCR4 signaling pathway to enhance immune recognition and clearance of GC (Created by BioRender). Abstract Gastric carcinoma (GC) remains a major global health challenge, requiring novel therapeutic approaches.
Qianqian Cao, Xiaolei Cheng, Rongbin Lv, Dianshui Sun, Jihua Wang, Runjia Fu, Rumei Gong, Yueying Xiao, Qin Liu, Xiaomei Li   +9 more
wiley   +1 more source

Individualized Target Fortification of Breast Milk with Protein, Carbohydrates, and Fat for Preterm Infants: Effect on Neurodevelopment. [PDF]

Nutrients
Rochow N, Leier NG, Weiss GA, Fusch G, Ali A, Bhatia A, El Helou S, Däbritz J, Fusch C.   +8 more
europepmc   +1 more source

Novel Antimicrobial Protein Fibroblast Growth Factor 8 Accelerates Skin Wound Healing via Directly Inhibiting Bacteria and Activating Glycolysis

Advanced Science, EarlyView.
Wound infections induce gcFGF8a expression, which subsequently executes direct antimicrobial activity to suppress local infection while simultaneously activating the FGFR4‐mediated ERK/AKT‐mTOR signaling cascade, thereby upregulating HIF1α and enhancing glycolysis. These coordinated actions synergistically promote tissue repair by eliminating pathogens
Ya‐Zhen Hu, Ting Wang, Chang‐Song Wu, Jie Wang, Xue‐Qing Han, Yong‐An Zhang, Xu‐Jie Zhang   +6 more
wiley   +1 more source

Risk Assessment of <i>Brucella</i> Exposure Through Raw Milk Consumption in India: One Health Implications and Control Strategies. [PDF]

Vet Sci
Sharma V, Singh BB, Brookes VJ.
europepmc   +1 more source

A Dual Approach with Organoid and CRISPR Screening Reveals ERCC6 as a Determinant of Cisplatin Resistance in Osteosarcoma

Advanced Science, EarlyView.
This study utilizes patient‐derived osteosarcoma organoids and CRISPR screening to identify ERCC6 and HNRNPM as key mediators of cisplatin resistance via the PI3K/AKT pathway and BAX alternative splicing. These findings provide novel insights and potential therapeutic targets for overcoming chemoresistance in osteosarcoma.
Ruiling Xu, Sai Zhu, Wenchao Zhang, Haodong Xu, Chao Tu, Honghui Wang, Lu Wang, Na He, Tang Liu, Xiaoning Guo, Xiaolei Ren, Zhihong Li   +11 more
wiley   +1 more source

Oropouche Virus (OROV) and Breastfeeding Safety: Analysis of Related Orthobunyaviruses for Mother-Infant Vertical Transmission in Breast Milk. [PDF]

Viruses
Schwartz DA, Vicente CR, Ververs M.
europepmc   +1 more source

Raw Equid Milk: A Potential Risk for Q Fever? [PDF]

Animals (Basel)
Mazzotta E, Natale A, Bellinati L, Ceglie L, Lucchese L, Kevenk TO, Menandro ML, Giacometti F, Alberghini L.   +8 more
europepmc   +1 more source

Development of simulated human milk ultrafiltrate (SHMUF) for analysis of native particles in human milk. [PDF]

Sci Rep
de Wolf JR, Paulusse JMJ, Bosschaart N.
europepmc   +1 more source

The effect of camel milk on house dust mite allergen induced asthma model in BALB/C mice. [PDF]

PLoS One
Rakhmatulina A, Kenenbay S, Abuova A, Kizatova M, Ibraikhan A, Makhmudov F, Mukashev A, Aitbaeva A, Abilkaiyr Z, Ibadullayeva G, Chomanov U, Murzabulatov A, Azimova S, Kulpiisova A, Bayantassova S, Aralbayev N, Imanbayeva N, Dikhanbayeva F, Burambayeva N, Smagulova N, Issimov A, White P.   +21 more
europepmc   +1 more source

Secretor and non-secretor human milk oligosaccharides differentially modulate immune response in the presence of cow's milk allergen β-lactoglobulin in an <i>in vitro</i> sensitization model. [PDF]

Front Immunol
Hellinga AH, Zuurveld M, Mank M, Kraneveld AD, Garssen J, Spann K, Bode L, Willemsen LEM, Van't Land B.   +8 more
europepmc   +1 more source