Results 291 to 300 of about 9,713,792 (350)

Paternal Obesity‐Induced H3K27me3 Elevation Leads to MANF‐Mediated Transgenerational Metabolic Dysfunction in Female Offspring

Advanced Science, EarlyView.
Paternal lifestyle and environmental exposures play a critical role in the offspring's health. The present study established a paternal obesity model and demonstrated that elevated H3K27me3 levels in sperm persist through the 8‐cell embryo stage. This epigenetic modification triggers transgenerational decrease of MANF, inducing ER stress and activating
Yajun Shi, Weisheng Li, Xi Yu, Yan Zhao, Dan Zhu, Yueyang Song, Zejun Zhao, Yannan Gu, Bin Wei, Lingjun Li, Dongyi Yu, Pengjie Zhang, Qinqin Gao, Miao Sun   +13 more
wiley   +1 more source

Correction: Cost analysis of establishing and operating the first human milk bank at Da Nang Hospital for women and children in Vietnam: an activity-based costing ingredients study

International Breastfeeding Journal
Minh V. Hoang, Tuan T. Nguyen, Anh T. Tran, Toan Q. Luu, Mai Q. Vu, Hoang T. Tran, Oanh T. X. Nguyen, Roger Mathisen   +7 more
doaj   +1 more source

Is breastfeeding 'exclusive'? Barriers facing global health professionals and proposed solutions. [PDF]

PLOS Glob Public Health
Schleiff MJ, Nambiar D, Yimer FN, Varallyay NI, Dalglish SL.   +4 more
europepmc   +1 more source

Viridicatol from the Deep‐Sea‐Derived Fungus Alleviates Bone Loss by Targeting the Wnt/SHN3 Pathway

Advanced Science, EarlyView.
Viridicatol (VDC), isolated from the deep‐sea‐derived fungus, enhances osteogenesis in vitro and in vivo by targeting Wnt/SHN3 signaling pathway. It can be delivered via engineered nanovesicles to mitigate bone loss of osteoporosis, fracture repair, and osteogenesis imperfecta.
Chun‐Lan Xie, Shang‐Hui Ye, Yu‐Ting Yue, Bao‐Hong Shi, Jing‐Ping Xu, Lian‐Jie Li, Zheng‐Biao Zou, Matthew B. Greenblatt, Na Li, Xian‐Wen Yang, Ren Xu   +10 more
wiley   +1 more source

¹H-NMR Lipidomics, Comparing Fatty Acids and Lipids in Cow, Goat, Almond, Cashew, Soy, and Coconut Milk Using NMR and Mass Spectrometry. [PDF]

Metabolites
Williams B, Hewage SPWR, Alexander D, Fernando H.   +3 more
europepmc   +1 more source

Biomimetic Nanoplatform for Targeted Rheumatoid Arthritis Therapy: Modulating Macrophage Niches Through Self‐Sustaining Positive Feedback‐Driven Drug Release Mechanisms

Advanced Science, EarlyView.
Rheumatoid arthritis is an incurable inflammatory autoimmune disease. The cleverly biomimetic nanoplatform integrates nanoenzymes and gene therapeutics and is sequentially modified by guanidinium‐based polymers and macrophage membranes, enhancing the gene silencing capability and reactive oxygen species scavenging efficiency through self‐sustaining ...
Huichao Xie, Xiaoyu Huang, Bao Li, Yongfeng Chen, Haoran Niu, Tong Yu, Shimei Yang, Shuxin Gao, Yutong Zeng, Tianzhi Yang, Yan Kang, Keda Zhang, Pingtian Ding   +12 more
wiley   +1 more source

Correction to: Higher bone mineral density at six years of age in very preterm-born infants fed human milk compared to formula feeding. A secondary analysis of an RCT. [PDF]

Eur J Pediatr
Toftlund LH, Beck-Nielsen SS, Agertoft L, Halken S, Zachariassen G.   +4 more
europepmc   +1 more source

Identification and Biological Evaluation of a Novel CLK4 Inhibitor Targeting Alternative Splicing in Pancreatic Cancer Using Structure‐Based Virtual Screening

Advanced Science, EarlyView.
Pancreatic cancer is a highly aggressive malignancy with limited treatment options. CLK4 regulates alternative splicing, contributing to cancer progression. This study establishes a computational model to identify CLK4 inhibitors, leading to compound 150441 (IC50: 21.4 nm).
Chun‐Lin Yang, Yi‐Wen Wu, Huang‐Ju Tu, Yun‐Hsuan Yeh, Tony Eight Lin, Tzu‐Ying Sung, Mu‐Chun Li, Shih‐Chung Yen, Jui‐Hua Hsieh, Ming‐Chin Yu, Sen‐Yung Hsieh, Hsing‐Pang Hsieh, Shiow‐Lin Pan, Kai‐Cheng Hsu   +13 more
wiley   +1 more source

mSphere of Influence: The maternal gut-mammary axis and its role in shaping neonatal health. [PDF]

mSphere
Langel SN.
europepmc   +1 more source