Results 201 to 210 of about 2,252,704 (261)

Polyphyllin I Alleviates Alcoholic Liver Disease via Modulation of the Phosphodiesterase 6D–Cyclic Guanosine Monophosphate–Protein Kinase G Axis

Phytotherapy Research, EarlyView.
ABSTRACT Alcoholic liver disease (ALD) is a multifaceted disorder in which oxidative injury, iron‐dependent ferroptosis, steatosis, and inflammation are closely intertwined. Consequently, therapeutic strategies targeting a single pathway often produce limited clinical benefits.
Hongyan Feng, Xuelian Yuan, Yawen Xie, Zhenni Xia, Zhaohui Guo, Xuesong Liu, Rong Li, Wenliang Wang   +7 more
wiley   +1 more source

Luteolin Alleviates Renal Fibrosis in Diabetic Kidney Disease via Activation of the Cx32‐Nrf2 Signaling Axis

Phytotherapy Research, EarlyView.
ABSTRACT Luteolin (Lut) is a flavonoid found in many medicinal plants, and previous studies have shown that it can slow the progression of diabetic kidney disease (DKD), although the mechanism is incompletely defined. This study asked whether Lut protects against DKD by acting on the connexin32 (Cx32)‐Nrf2 signaling axis to suppress ferroptosis and ...
Shuang Liang, Qiudong Nong, Yeyi Chen, Yuan He, Ting Feng, Guitian Chen, Qingshao Zhang, Zhiying Liu, Guoqi Ou, Dezhe Tang, Yang Jiao, Zhiquan Chen   +11 more
wiley   +1 more source

Oxyberberine Ameliorates Type 2 Diabetic Osteoporosis Through Sirtuin 3‐Associated Regulation of Autophagy and Ferroptosis in Bone Marrow Mesenchymal Stem Cells

Phytotherapy Research, EarlyView.
Schematic overview of the in vivo and in vitro experimental designs used to investigate the protective effects of oxyberberine (OBB) against type 2 diabetic osteoporosis, including C‐Z treatment, Sirt3 knockdown, and assessments of osteogenesis, autophagy, oxidative stress, and ferroptosis. ABSTRACT Type 2 diabetic osteoporosis (T2DOP) is characterized
Jianan Huang, Baihao Chen, Hua Zhang, Junzheng Yang, Jiacong Xiao, Chenhui Meng, Yanchao An, Kai Meng, Baohua Wang, Zhantian An, Peng Chen   +10 more
wiley   +1 more source

Betulinic Acid Counteracts Statin‐Induced PCSK9 Upregulation Through FXR/SHP‐Associated Signaling

Phytotherapy Research, EarlyView.
Betulinic acid attenuates atorvastatin‐induced increases in PCSK9 expression and secretion while maintaining or increasing LDLR expression in hepatocyte‐derived cells. Mechanistic studies support the involvement of FXR/SHP signaling and show increased SHP–SREBP2 association.
Chan‐Woong Park, Mingoo Bae, Pureum Kang, Na Young Lee, Ja Hyun Koo, Young Hee Choi, Young‐Won Chin   +6 more
wiley   +1 more source

Financial Inclusion for Smallholders: Integrating a Resource Nexus Approach Into Agricultural Finance Systems

Sustainable Development, EarlyView.
ABSTRACT Smallholder farmers remain structurally excluded from the current agricultural finance system. Existing research in this area examines financial inclusion through fragmented environmental, social, and economic lenses, limiting system‐level understanding.
Vaibhav Aggarwal, Matthias Walz, Edeltraud Guenther   +2 more
wiley   +1 more source

Opportunities for Australia Amid China's Carbon‐Neutral Transition: Input–Output Approach With Analysis of Australian Renewable Potential

Sustainable Development, EarlyView.
ABSTRACT A major transformation in China's energy mix is underway as the country pursues carbon neutrality by 2060, posing significant structural challenges for Australia as a major exporter of carbon‐intensive resources. This study examines the economic impacts of China's decarbonisation on Australia by applying static and dynamic input–output (IO ...
Jinyong (Edward) Sung
wiley   +1 more source

Affordable and Clean Energy: CO2 Emissions, Resilience and Inequality

Sustainable Development, EarlyView.
ABSTRACT Sustainable development means building the resilience of both people and the planet. It includes implementing strategies which reduce emissions while also enabling more vulnerable households to transition to clean and affordable energy. This paper examines household CO2 emissions in Ireland to highlight those who emit most and least in key ...
Nessa Winston, Monika da Silva Pedroso, Ciarán Mac Domhnaill   +2 more
wiley   +1 more source

Symbols of Climate Action: Audit Labor and the Production of Carbon Credits

Economic Anthropology, EarlyView.
ABSTRACT Voluntary carbon markets (VCMs) are promoted as tools for financing climate mitigation, yet their effectiveness and credibility remain contested. This article examines how carbon credits are produced and destabilized as symbols of climate action, emphasizing the forms of ecological and audit labor that sustain their legitimacy.
Diego Silva Garzón
wiley   +1 more source

[The milk bank].

Boletin medico del Hospital Infantil de Mexico, 2003
openaire   +1 more source

ANGPT2 Drives Thyroid Cancer Progression Through PI3K/AKT Signaling and Correlates With Poor Prognosis and Immune Infiltration

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives Angiopoietin‐2 (ANGPT2) is known to participate in tumor progression and immune modulation across multiple malignancies. Nevertheless, its expression pattern, prognostic value, and biological function in thyroid cancer (THCA) have not been comprehensively investigated.
Han Chen, Lin Wang, Ji‐Sheng Zhang, Xu‐Dong Yan, Long‐Gang Yu, Yan Jiang   +5 more
wiley   +1 more source